AI Article Synopsis
- The study aimed to investigate how neonatal respiratory support affects lung function in very low birth weight children with bronchopulmonary dysplasia (BPD) as they reach school age.
- Researchers reviewed data from 78 BPD children who had their lung function assessed at ages 8-9, finding that 31% exhibited abnormalities in lung function, correlated with the type of respiratory support they received.
- Key findings included that antenatal steroid use reduced the risk of lung function abnormalities, while needing positive-pressure support at 37 weeks of postmenstrual age was linked to a higher risk of abnormal lung function.
Article Abstract
Objective: To elucidate the relationship between abnormal lung function (LF) at school age and neonatal respiratory support in very low birth weight children with bronchopulmonary dysplasia (BPD).
Study Design: We retrospectively examined 78 BPD children whose LF was evaluated at 8-9 years. LF abnormalities were defined by reduced values of spirometric parameters. Adjusted odds ratios (aORs) for abnormal LF by the type and postmenstrual age (PMA) of respiratory support were calculated using logistic regression analysis after controlling perinatal factors.
Results: Overall, 24 (31%) patients had LF abnormalities. Antenatal steroid use was associated with a decreased risk of abnormal LF [aOR, 0.31; 95% CI, 0.09-0.92]. Requiring positive-pressure support at 37 weeks' PMA correlated with abnormal LF [aOR, 4.58; 95% CI, 1.15-21.90]; whereas only low-flow oxygen at any PMA did not.
Conclusion: Requiring positive-pressure support at 37 weeks' PMA could be an indicator of abnormal LF at school age.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/s41372-023-01609-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!