In order to realize the magnetization of hydrogel mixed with NdFeB powder, a magnetization drive coil based on a Helmholtz coil is designed in this paper. The 3D model of the magnetic field system is drawn by the Maxwell software 3D module, and the influence of different factors on the magnetic induction intensity is analyzed to obtain the optimized structure of the magnetization drive coil; then, the central magnetic induction intensity and magnetic induction line distribution density of the magnetization drive coil and Helmholtz coil are compared to verify the reliability of the structure optimization. The results show that the central magnetic induction intensity is the highest when the distance between the auxiliary coils is 70 mm, the central magnetic induction intensity of the magnetized drive coil is significantly higher than that of the Helmholtz coil when the number of turns is the same, and the central magnetic induction intensity of the optimized magnetized drive coil can reach 1.37 T with a more uniform and dense magnetic induction line distribution. After building the magnetization drive coil, the magnetic induction intensity of the center of the magnetization drive coil can reach 1.34 T by a handheld digital Gauss meter test, and the error is no more than 2% with the simulation result. This design approach provides a reference for the structural design and operating characteristics analysis of magnetized drive coils and shortens the design cost and development cycle of magnetized drive coils.
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http://dx.doi.org/10.3390/mi14010152 | DOI Listing |
Cureus
December 2024
Department of Neurological Surgery, Ryofukai Satoh Neurosurgical Hospital, Fukuyama, Hiroshima, JPN.
Coil embolization of cerebral aneurysms often encounters challenges in achieving complete filling of the aneurysm sac due to complex shapes and hemodynamic factors, frequently resulting in the formation of a residual cavity (RC) at the aneurysm neck. The hemodynamic mechanisms underlying RC formation and growth, however, remain poorly understood. Computational fluid dynamics (CFD) analysis, combined with silent MRA free from contrast agents and metal artifacts, offers a promising approach to elucidate these mechanisms, potentially enhancing the clinical management of cerebral aneurysms post-coiling.
View Article and Find Full Text PDFAnimals (Basel)
December 2024
Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
The social complexity hypothesis suggests that complex social interactions drive the evolution of sophisticated communicative signals. While the relationship between social communication and the complexity of sound and color signals has been extensively studied, the correlation between social communication and movement-based visual signal complexity remains underexplored. In this study, we selected the Asian agamid lizard, , as our model system.
View Article and Find Full Text PDFJ Chem Phys
January 2025
CNRS, Laboratoire PHENIX (Physicochimie des Electrolytes et Nanosystèmes Interfaciaux), Sorbonne Université, 4 Place Jussieu, 75005 Paris, France.
By means of a minimal physical model, we investigate the interplay of two phase transitions at play in chromatin organization: (1) liquid-liquid phase separation within the fluid solvating chromatin, resulting in the formation of biocondensates; and (2) the coil-globule crossover of the chromatin fiber, which drives the condensation or extension of the chain. In our model, a species representing a domain of chromatin is embedded in a binary fluid. This fluid phase separates to form a droplet rich in a macromolecule (B).
View Article and Find Full Text PDFbioRxiv
December 2024
Department of Biochemistry and Molecular Genetics, University of Colorado, Denver - Anschutz Medical Campus.
Organisms with smaller genomes often perform multiple functions using one multi-subunit protein complex. The Silent Information Regulator complex (SIRc) carries out all of the core functions of heterochromatin. SIR complexes first drive the initiation and spreading of histone deacetylation in an iterative manner.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Suite 523, Bridgeside Point II, 450 Technology Drive, Pittsburgh, PA, 15219, USA.
Overexpression of the myeloid Src-family kinases Fgr and Hck has been linked to the development of acute myeloid leukemia (AML). Here we characterized the contribution of active forms of these kinases to AML cell cytokine dependence, inhibitor sensitivity, and AML cell engraftment in vivo. The human TF-1 erythroleukemia cell line was used as a model system as it does not express endogenous Hck or Fgr.
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