Selective laser sintering (SLS) is one of the key additive manufacturing technologies that can build any complex three-dimensional structure without the use of any special tools. Thermal modeling of this process is required to anticipate the quality of the manufactured parts by assessing the microstructure, residual stresses, and structural deformations of the finished product. This paper proposes a framework for the thermal simulation of the SLS process based on the discrete element method (DEM) and numerically generated in Python. This framework simulates a polyamide 12 (PA12) particle domain to describe the temperature evolution in this domain using simple interaction laws between the DEM particles and considering the exchange of these particles with the boundary planes. The results obtained and the comparison with the literature show that the DEM frame accurately captures the temperature distribution in the domain scanned by the laser. The effect of laser power and projection time on the temperature of PA12 particles is investigated and validated with experimental settings to show the reliability of DEM in simulating powder-based additive manufacturing processes.
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http://dx.doi.org/10.3390/ma16020753 | DOI Listing |
Phys Chem Chem Phys
January 2025
Université de Lorraine, CNRS, LRGP, F-54000 Nancy, France.
Stereochemistry plays a key role in both fundamental chemical processes and the dynamics of a large set of molecular systems of importance in chemistry, medicine and biology. Predicting the chemical transformations of organic precursors in such environments requires detailed kinetic models based on laboratory data. Reactive intermediates play a critical role in constraining the models but their identification and especially their quantification remain challenging.
View Article and Find Full Text PDFChemphyschem
January 2025
Goethe-Universität Frankfurt am Main, Physical and Theoretical Chemistry, Max von Laue-Straße 7, 60438, Frankfurt am Main, GERMANY.
The light-sensing activity of phytochromes is based on the reversible light-induced switching between two isomerization states of the bilin chromophore. These photo-transformations may not necessarily be only unidirectional, but could potentially branch back to the initial ground state in a thermally driven process termed shunt. Such shunts have been rarely reported, and thus our understanding of this process and its governing factors are limited.
View Article and Find Full Text PDFPhys Chem Chem Phys
January 2025
School of Advanced Manufacturing Engineering, Chongqing University of Posts and Telecommunications, Chongqing 400065, China.
This paper presents a multiscale computational model, 'micro-to-meso-to-macro', to simulate polydopamine coated gold nanoparticles (AuNP@PDA) for assisted tumor photothermal therapy (PTT). The optical properties, mainly refractive index, of the PDA unit molecules are calculated using the density functional theory (DFT) method in this multiscale model. Subsequently, the thermodynamic properties, including thermal conductivity and heat capacity, of the PDA cells and AuNP@PDA particles are calculated using molecular dynamics (MD) simulation.
View Article and Find Full Text PDFFront Microbiol
December 2024
Oniris VetAgroBio, INRAE, SECALIM, Nantes, France.
Our study aims to assess the thermal inactivation of non-proteolytic type B spores in a plant-based fish and to evaluate the potential of alternative heat treatments at temperatures below the safe harbor guidelines established for vacuum-packed chilled products of extended durability. First, the heat resistance of the spore suspension was determined using capillary tubes in potassium phosphate buffer at 80°C. The D value was estimated to be 0.
View Article and Find Full Text PDFTheranostics
January 2025
College of Pharmacy, Seoul National University, Seoul 08826, South Korea.
Hypoxia is a major obstacle in the treatment of solid tumors because it causes immune escape and therapeutic resistance. Drug penetration into the hypoxic regions of tumor microenvironment (TME) is extremely limited. This study proposes using the unidirectional fluid flow property of low-intensity pulsed ultrasound (LIPUS) to overcome drug penetration limitations in the TME.
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