Analysis of : A Long Non-Coding RNA Hosting , Whose Loss Contributes to Prader-Willi Syndrome Etiology.

The Small Nucleolar Host Gene 14 () is a host gene for small non-coding RNAs, including the small nucleolar C/D box RNA encoding locus. Large deletions of the locus, as well as microdeletions of the locus, lead to the neurodevelopmental genetic disorder Prader-Willi syndrome. This review will focus on the gene, its expression patterns, its role in human cancer, and the possibility that single nucleotide variants within the locus contribute to human phenotypes in the general population. This review will also include new in silico data analyses of the locus and new in situ RNA expression patterns of the Snhg14 RNA in mouse midbrain and hindbrain regions.