AI Article Synopsis
- Hepatocellular carcinoma (HCC) is the most common type of liver cancer, with liver resection and transplantation being potential curative methods, but recurrence rates can complicate prognosis.
- Treatment strategies for recurrent HCC (rHCC) are underexplored despite the validity of options like redo hepatectomy and salvage liver transplantation for certain patients.
- The review focuses on the role of surgical approaches for rHCC in the context of advancing personalized medicine and new systemic therapies.
Article Abstract
Hepatocellular carcinoma (HCC) is the most common primary liver cancer, and both liver resection and liver transplantation are considered potentially curative options. However, high recurrence rates affect the prognosis depending both on the primary HCC pathology characteristics or on the type and time of the relapse. While great attention has been usually posted on treatment algorithms for the first HCC, treatment algorithms for recurrent HCC (rHCC) are lacking. In these cases, surgery still represents a curative option with both redo hepatectomy and/or salvage liver transplantation, which are considered valid treatments in selected patients. In the current era of personalised medicine with promises of new systemic-targeted immuno-chemotherapies, we wished to perform a narrative review of the literature on the role of surgical strategies for rHCC.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856445 | PMC |
| http://dx.doi.org/10.3390/cancers15020508 | DOI Listing |
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