In this work, by considering superstatistics we investigate the short-range correlations (SRCs) and the fluctuations in the distribution of lengths of strings of nucleotides. To this end, a stochastic model provides the distributions of the size of the exons based on the q-Gamma and inverse q-Gamma distributions. Specifically, we define a time series for exon sizes to investigate the SRC and the fluctuations through the superstatistics distributions. To test the model's viability, we use the Project Ensembl database of genes to extract the time evolution of exon sizes, calculated in terms of the number of base pairs (bp) in these biological databases. Our findings show that, depending on the chromosome, both distributions are suitable for describing the length distribution of human DNA for lengths greater than 10 bp. In addition, we used Bayesian statistics to perform a selection model approach, which revealed weak evidence for the inverse q-Gamma distribution for a considerable number of chromosomes.
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http://dx.doi.org/10.1103/PhysRevE.106.064407 | DOI Listing |
Entropy (Basel)
September 2024
Departamento de Física, Universidade Federal do Rio Grande do Norte, Natal 59072-970, Brazil.
The short and long statistical correlations are essential in the genomic sequence. Such correlations are long-range for introns, whereas, for exons, these are short. In this study, we employed superstatistics to investigate correlations and fluctuations in the distribution of nucleotide sequence lengths of the family.
View Article and Find Full Text PDFPhys Rev E
December 2022
Departamento de Física, Universidade Federal do Rio Grande do Norte, Natal - RN, 59072-970, Brasil and Programa de Pós-Graduação em Física, Universidade do Estado do Rio Grande do Norte, Mossoró - Rio Grande do Norte, 59610-210, Brasil.
In this work, by considering superstatistics we investigate the short-range correlations (SRCs) and the fluctuations in the distribution of lengths of strings of nucleotides. To this end, a stochastic model provides the distributions of the size of the exons based on the q-Gamma and inverse q-Gamma distributions. Specifically, we define a time series for exon sizes to investigate the SRC and the fluctuations through the superstatistics distributions.
View Article and Find Full Text PDFActa Physiol Scand
March 1996
Biology Department, Marquette University, Milwaukee, Wisconsin 53233, USA.
The causative factors in muscle fatigue are multiple, and vary depending on the intensity and duration of the exercise, the fibre type composition of the muscle, and the individual's degree of fitness. Regardless of the aetiology, fatigue is characterized by the inability to maintain the required power output and the decline in power can be attributed to a reduced force and velocity. Following high-intensity exercise, peak force has been shown to recover biphasically with an initial rapid (2 min) recovery followed by a slower (50 min) return to the pre-fatigued condition.
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