Pharmacological management of disease by overcoming structural adversity.

Cell Chem Biol

Departments of Pathology and Immunology, Molecular & Cellular Biology, and Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

Published: January 2023

In this issue of Cell Chemical Biology, Sun et al. utilize computational and protein expression analyses, plus pharmacological proteostasis network activation, to simultaneously correct two genetic diseases linked to a single protein rather than modify the responsible DNA.

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Source
http://dx.doi.org/10.1016/j.chembiol.2022.12.008DOI Listing

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