Radioisotope bone scans to search for occult skeletal metastases at initial staging were obtained in 540 patients with invasive cervical carcinoma admitted to the Gynecological Oncology Unit of the Tygerberg Hospital over a 36-month period. Positive scans were reported in 55 (10.2%) patients but subsequent radiographic examination revealed that of these, 43 were false positive. The 11 patients with bony metastases were all initially classified as Stage III or IV disease irrespective of the bone scan and the positive scans influenced the clinical staging in only 6 (1.1%) patients. All the bone scans in the 210 patients with clinical Stage I or II disease were negative. Bone scanning does not seem warranted at initial staging in Stage I or II invasive cervical carcinoma.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/0090-8258(87)90216-2 | DOI Listing |
Ann Thorac Surg Short Rep
September 2023
Division of Thoracic Surgery, Department of Surgery, The Jikei University School of Medicine, Minatoku, Tokyo, Japan.
The combination of thoracoscopic and transmanubrial approaches provides good visualization and maneuverability of the cervicothoracic junction area. Here we report the case of a young woman with a mediastinal tumor extending to the neck who first underwent a thoracoscopic approach followed by a transmanubrial approach. This procedure was superior in terms of technical advantages and preserved function as well as minimally invasive and cosmetically pleasing.
View Article and Find Full Text PDFIndian J Nucl Med
November 2024
Department of General Surgery, King George's Medical University, Lucknow, Uttar Pradesh, India.
Background: Distribution and quantification of extra-pulmonary tuberculosis and elicitation of response antitubercular therapy via F18-Fluorodeoxyglucose Positron Emission-based Tomography/ Computed Tomography(F18-FDG PET/CT).
Materials And Methods: This was a prospective Pilot study. In this study 30 patients of age between 15 to 36 years(mean 26.
iScience
January 2025
Department of Biology, University of Copenhagen, 2100 Copenhagen, Denmark.
Chromothripsis, a hallmark of cancer, is characterized by extensive and localized DNA rearrangements involving one or a few chromosomes. However, its genome-wide frequency and characteristics in urothelial carcinoma (UC) remain largely unknown. Here, by analyzing single-regional and multi-regional whole-genome sequencing (WGS), we present the chromothripsis blueprint in 488 UC patients.
View Article and Find Full Text PDFCardiovasc Diagn Ther
December 2024
Department of Ultrasound, Zhejiang Cancer Hospital, Hangzhou, China.
Background: About 30% of ischemic strokes do not have a clear cause, which is called cryptogenic stroke (CS). Increasing evidence suggests a potential link between CS and right-to-left shunt (RLS). RLS may lead to CS via paradoxical embolic mechanism.
View Article and Find Full Text PDFKaohsiung J Med Sci
January 2025
Department of Neck Surgery, Sanming First Hospital Affiliated to Fujian Medical University, Sanming, China.
Metastasis is the trigger of death in anaplastic thyroid cancer (ATC) patients, yet the specific mechanisms at play are still largely enigmatic. While the involvement of LARP1 in the metastatic process of various cancers has been documented, there is a noticeable gap in the literature regarding its potential influence on ATC metastasis. Molecular studies probed LARP1 expression within ATC cells, with subsequent in vitro experiments examining the effects of LARP1 on ATC cell metastasis and the mTOR signaling cascade.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!