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Water-Mediated On-Demand Detachable Solid-State Adhesive of Porous Hydroxyapatite for Internal Organ Retractions.
Adv Healthc Mater
July 2024
Department of Biomaterials, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-cho, Kita-ku, Okayama City, Okayama, 700-8558, Japan.
Article Synopsis
- Novel adhesives made from porous hydroxyapatite (HAp) ceramics provide a new method for surgical procedures involving biological tissues.
- These adhesives work by allowing water to move from soft tissues into their porous structure, which helps them effectively attach to different tissue types under various hydration conditions.
- Demonstrated during surgeries on porcine livers, these HAp adhesive devices show strong holding capabilities and can be easily detached when needed, indicating their potential use as internal organ retractors in laparoscopic surgeries.
Water-Mediated Intramolecular Cyclization/Oxidation of α-Carbonyl Sulfur Ylides: Synthesis of Corey-Chaykovsky Reagent Type Heterocycles.
Org Lett
October 2021
The State Key Laboratory of Geohazard Prevention and Geoenvironment Protection, College of Materials, Chemistry & Chemical Engineering, Chengdu University of Technology, Chengdu 610059, People's Republic of China.
A new class of Corey-Chaykovsky reagent type five-membered heterocycles with an oxosulfonium ylide moiety has been synthesized by the water-mediated intramolecular cyclization/oxidation of α-carbonyl sulfur ylides generated from sulfonium salts under mild conditions.
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