Antiproliferative -abietane diterpenoids from .

Nat Prod Res

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, People's Republic of China.

Published: December 2023

Euphorfinoids M and N ( and ), two previously undescribed -abietane diterpenoids, together with seven known analogues (-), were isolated from the roots of wild . Their structures were elucidated by spectroscopic analysis, including extensive NMR, HR-ESIMS, ECD, and comparison with structurally related known analogues. Bioassays against proliferative effects of HeLa cell line showed that compound was the most active with IC 3.62 ± 0.31 μM.

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Source
http://dx.doi.org/10.1080/14786419.2023.2169686DOI Listing

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