Periarthropathies The term "periarthropathy" stands for various pathologies "around" the joint and its structures, without a clear and generally accepted definition. This article tries to outline this theme and offers some examples in the section "ausgewählte Krankheitsbilder".
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Periarthropathies The term "periarthropathy" stands for various pathologies "around" the joint and its structures, without a clear and generally accepted definition. This article tries to outline this theme and offers some examples in the section "ausgewählte Krankheitsbilder".
View Article and Find Full Text PDF[Chronic pain syndrome in diseases of periarticular tissues].
Zh Nevrol Psikhiatr Im S S Korsakova
September 2020
Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia.
The search for an effective method of treating diseases of the musculoskeletal system is a rather actual problem for a practicing physician nowadays in connection with the modern lifestyle of most people. A prolonged stay in the same position, as a rule, leads to overstrain of the capsule-joint complexes, and, as a consequence, to the development of degenerative changes in the joints and periarticular tissues. These changes can manifest themselves clinically in the form of a chronic or acute pain syndrome.
View Article and Find Full Text PDF[5-HT3 receptor antagonist als analgetics in rheumatic diseases].
Z Rheumatol
October 2006
Hochrhein-Institut für Rehabilitationsforschung, Bad Säckingen.
Various rheumatic diseases like fibromyalgia, systemic inflammatory rheumatic disorders and localized diseases, such as arthritides and activated arthroses, tendinopathies and periarthropathies, as well as trigger points can be improved considerably by treatment with the 5-HT3 receptor antagonist tropisetron. Particularly in the latter group of diseases, local injections have done surprisingly rapid analgesic action. This effect matches that of local anesthetics, but lasts considerably longer and is comparable to local injections of local anesthetics combined with corticosteroids.
View Article and Find Full Text PDFPhysiology and pathophysiology of the 5-HT3 receptor.
Scand J Rheumatol Suppl
December 2004
Department of Pharmacology, Regensburg Medical School, Regensburg, Germany.
The 5-HT3 receptor is a ligand-gated cation channel located in the central and peripheral nervous system; it has also been detected on a variety of other cells. In the periphery, it is found on autonomic neurons and on neurons of the sensory and enteric nervous system. In the CNS, the 5-HT3 receptor has been localized in the area postrema, nucleus tractus solitarii, nucleus vaudatus, nucleus accumbens, amygdala, hippocampus, entorhinal, frontal, cingulate cortex, and in the dorsal horn ganglia.
View Article and Find Full Text PDF[Local treatment of rheumatic diseases with the 5-HT3 receptor antagonist tropisetron].
Schmerz
June 2003
Hochrhein-Institut für Rehabilitationsforschung, Bad Säckingen.
Local injection of the 5-HT3 receptor antagonist tropisetron manifests a distinct analgesic effect in various local diseases of the locomotor system such as tendinopathies, peri-arthropathies,myofascial pain syndrome, in trigger points, and in inflammatory joint processes.This effect corresponds to that exerted by local anesthetics in general use such as lidocaine and prilocaine among others, but the effect lasts considerably longer. The reason for this finding is found in a simultaneous antiphlogistic effect of the 5-HT3 receptor antagonist as evidenced by animal experiments and clinical data.
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