The mortality gap between former East and West Germany decreased rapidly in the decade following the reunification of the country in 1990. However, because no previous study has estimated life expectancy (e0) over time for all German districts, the extent of mortality convergence across districts and its determinants are largely unknown. We used a novel relational Bayesian model to estimate district e0 in Germany during 1997-2016, examined mortality convergence using a novel convergence groups approach, and explored the role of selected district characteristics in the process. Differences in e0 between German districts decreased for both sexes during 1997-2016, mainly driven by rapid mortality improvements in eastern German districts. However, considerable heterogeneity in district-level e0 trajectories within federal states was evident. For example, district clusters in northwestern Germany showed increasing e0 disadvantage, which led to a north-south divergence in mortality. A multinomial regression analysis showed a robust association between the e0 trajectory and the district-level tax base and long-term unemployment but not with hospital density. Thus, an equitable "leveling up" of health seems possible with policies investing in places and the people who inhabit them.
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http://dx.doi.org/10.1215/00703370-10422945 | DOI Listing |
J Gastric Cancer
January 2025
Department of Surgery, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.
Purpose: Since 1995, the Korean Gastric Cancer Association (KGCA) has been periodically conducting nationwide surveys on patients with surgically treated gastric cancer. This study details the results of the survey conducted in 2023.
Materials And Methods: The survey was conducted from March to December 2024 using a standardized case report form.
Sci Rep
January 2025
Division of Nephrology and Hypertension, Department of Internal Medicine, Inha University Hospital, Inha University College of Medicine, 27 Inhang-ro, Jung-gu, Incheon, 2332, Republic of Korea.
Lean body mass (LBM) serves as an indicator of muscle mass in body composition. Recently, studies have revealed increased mortality rates in dialysis patients with low LBM. However, studies analyzing the impact of age on LBM and mortality in dialysis patients remain limited.
View Article and Find Full Text PDFJ Clin Sleep Med
January 2025
Department of Convergence Healthcare Medicine, Ajou University, Suwon, Republic of Korea.
Study Objectives: Undiagnosed or untreated moderate to severe obstructive sleep apnea (OSA) increases cardiovascular risks and mortality. Early and efficient detection is critical, given its high prevalence. We aimed to develop a practical and efficient approach for obstructive sleep apnea screening, using simple facial photography and sleep questionnaires.
View Article and Find Full Text PDFBiomed Pharmacother
January 2025
College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, South Korea; Gradutate Program in Innovative Biomaterials Convergence, Ewha Womans University, Seoul 03760, South Korea. Electronic address:
SMEPPI is a small molecule synthesized as a derivative of KR-62980 that has anti-diabetic and anti-inflammatory activities. Despite the established physiological effects of KR-62980, the effects and benefits of SMEPPI remain largely unexplored. This study investigated the immunomodulatory functions of SMEPPI on macrophages and inflammatory diseases.
View Article and Find Full Text PDFHarm Reduct J
January 2025
Salvation Army Centre for Addiction Services and Research, University of Stirling, Stirling, Scotland.
Background: Scotland currently has amongst the highest rates of drug-related deaths in Europe, leading to increased advocacy for safer drug consumption facilities (SDCFs) to be piloted in the country. In response to concerns about drug-related harms in Edinburgh, elected officials have considered introducing SDCFs in the city. This paper presents key findings from a feasibility study commissioned by City of Edinburgh Council to support these deliberations.
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