AI Article Synopsis
- Cryptococcosis is an opportunistic infection that can occur in individuals with immune disorders, such as those caused by thymomas, which can lead to T cell immunodeficiency.
- A 63-year-old male was diagnosed with cutaneous cryptococcosis, linked to a type B3 thymoma found during tests for lymphopenia, necessitating surgical removal.
- Successful treatment of the cryptococcal infection was achieved with azole therapy, emphasizing the importance of a multidisciplinary approach in diagnosing and managing such rare cases.
Article Abstract
Background And Purpose: Cryptococcosis is a known opportunistic infection. Thymomas are known to cause immune dysregulation. We describe an atypical case of cutaneous cryptococcosis in a patient with acquired T cell immunodeficiency that has been found to be secondary to a type B3 thymoma with progression to carcinoma.
Case Report: A 63-year-old male presented with a chronic skin lesion confirmed as on biopsy and an incidental mediastinal mass found during infectious work-up for the notable cluster of differentiation 4 (CD4)+ lymphopenia. This led to the diagnosis of a type B3 thymoma requiring resection. The cryptococcal lesion was treated successfully with azole therapy.
Conclusion: is an opportunistic infection rarely associated with isolated T cell immunodeficiency due to thymomas. A multidisciplinary approach and understanding of the pathogenicity of and the immunological effect of thymic dysfunction are paramount to diagnosis and treatment.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825796 | PMC |
| http://dx.doi.org/10.18502/CMM.8.2.10334 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!