This work details a polyolefin-elastomer-based binder system to prepare fused filament fabrication (FFF) filaments and print cores for coils for electrical engines. The processability, homogeneity, and thermal properties of the polyolefin-elastomer-based filaments are explored. A two-step debinding and sintering process was established for manufacturing dense iron parts. Results indicate the developed filaments possess superior printing and sintering (at 900°C) performance, yielding only 20% weight loss by polymer decomposition and 14 vol.% shrinkage. This indicates that the FFF technique potentially enables printing of innovative electric motor designs. The designed FFF filaments could be loaded with 80 wt.% Fe powder while keeping a decent melt-viscosity for the printing process. Due to the high metal loading, dense iron parts could be sintered without bending or deformation.
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http://dx.doi.org/10.1089/3dp.2020.0136 | DOI Listing |
Int J Pharm
December 2024
Beijing Institute of Radiation Medicine, Beijing 100850, China. Electronic address:
Cannabidiol (CBD) is widely used to alleviate the syndromes of epilepsy. However, the marketed oral CBD formulation has the prominent first-pass effect. Here, a cannabidiol-loaded hollow suppository (CHS) was developed using three-dimensional (3D) printing technology.
View Article and Find Full Text PDFDrug Dev Ind Pharm
December 2024
Gazi University, Faculty of Pharmacy, Department of Pharmaceutical Technology, 06330 Etiler, Ankara, Türkiye.
Introduction: This study aims to develop immediate release tablet formulations of lornoxicam (LRX) using hot melt extrusion (HME)-based fused deposition modelling (FDM) focusing on the adjustment of drug release by arranging infill densities and evaluating microcrystalline cellulose II (MCC II) as a disintegrating agent for HME-FDM purposes. LRX is a poorly soluble drug that exhibits pH-dependent solubility with a high thermal degradation temperature. These characteristics make it an ideal model drug for the HME-based FDM technique.
View Article and Find Full Text PDFRSC Med Chem
December 2024
Department of Chemistry and Physics, College of Sciences and Mathematics, Arkansas State University Jonesboro Arkansas 72467 USA
Melanoma, the most fatal form of skin cancer, often becomes resistant to the current therapeutic approaches in most patients. To explore new treatment options, fused thiazole derivatives were synthesized, and several of these compounds demonstrated potent anti-melanoma activity both and . These compounds exhibited significant cytotoxicity against melanoma cell lines at low concentrations.
View Article and Find Full Text PDFMaterials (Basel)
December 2024
Institute of Machinery, Materials and Transport, Peter the Great Saint Petersburg Polytechnic University, Politechnicheskaya ul. 29, 195251 Saint Petersburg, Russia.
In recent years, 3D printing has emerged as a promising technology in energy storage, particularly for the fabrication of Li-ion battery electrodes. This innovative manufacturing method offers significant material composition and electrode structure flexibility, enabling more complex and efficient designs. While traditional Li-ion battery fabrication methods are well-established, 3D printing opens up new possibilities for enhancing battery performance by allowing for tailored geometries, efficient material usage, and integrating multifunctional components.
View Article and Find Full Text PDFMaterials (Basel)
November 2024
Faculty of Mechanical Engineering and Ship Technology, Department of Manufacturing and Production Engineering, Institute of Machine and Materials Technology, Gdańsk University of Technology, G. Narutowicza Str. 11/12, 80-233 Gdańsk, Poland.
Nowadays, high requirements imposed by mechanical components make it necessary to develop modern production methods. Additive technologies have been dynamically developing in recent years, showing many advantages associated with the fabrication of elements with complex geometries and structures. One of the areas where the potential of additive technologies is exploited is the rapid tooling sector, which is based on the rapid production of tools and components used in various manufacturing methods.
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