Proteome-based insights for IDH-mutant glioma classification.

Cell Rep Med

Department of Neurosurgery and Laboratory of Brain Tumor Immunotherapy and Biology, Department of BioMedicine, University Hospital Basel and University of Basel, Hebelstrasse 20, 4031 Basel, Switzerland. Electronic address:

Published: January 2023

In this issue, Bader et al. characterize the proteomes of diffuse glioma brain tumors by liquid chromatography mass spectrometry and classify isocitrate dehydrogenase (IDH)-mutant gliomas into two subtypes, which differ in oncogenic pathways and aerobic/anaerobic energy metabolism.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873937PMC
http://dx.doi.org/10.1016/j.xcrm.2022.100909DOI Listing

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