The study aims to explore the burden of postpartum depression among COVID-19-infected mothers and stressor factors. A single-centre observational cohort study was conducted in South India to evaluate postpartum depression among 106 COVID-19-infected women who delivered from December 2020 to May 2021. Also, stressor factors related to COVID-19 infection were figured out to analyse their role in depression. Almost half of the COVID-19-infected mothers had a global EPDS score ≥ 10 and were at risk of depression during the pandemic. The depressive symptoms were not confined to the immediate postpartum period, but significantly impacted mothers until 6 months following childbirth. SYNOPSIS: COVID-19 infection not only affects the physical well-being but also adversely affects the mental health of the infected persons. Postpartum mothers who require the utmost care and support, are facing social deprivation due to the COVID-19 pandemic. This triggers the already fragile mental state of postpartum women and may worsen the level of depression.
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http://dx.doi.org/10.1016/j.ajp.2023.103452 | DOI Listing |
BMC Med Res Methodol
January 2025
Department of Women's and Children's Health - Obstetric & Reproductive Health Research, Uppsala University, Uppsala, 751 85, Sweden.
Background: Peripartum depression is a common but potentially debilitating pregnancy complication. Mobile applications can be used to collect data throughout the pregnancy and postpartum period to improve understanding of early risk indicators.
Aim: This study aimed to improve understanding of why women drop out of a peripartum depression mHealth study, and how we can improve the app design.
J Affect Disord
January 2025
Department of Health Sciences, University Medical Center Groningen, University of Groningen, the Netherlands.
Objectives: To assess the association of early and late postpartum maternal mental health with infants' health related quality of life (HRQoL).
Methods: The study was embedded within the POST-UP trial (n = 1843). Infants' HRQoL was assessed with the Infant and Toddler Quality of Life Questionnaire Short Form-47 at ages 1 month (1 m), and 12 m.
J Affect Disord
January 2025
Department of Psychiatry and Medical Psychology, OLVG, P.O. Box 95500, 1090 HM Amsterdam, the Netherlands; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit van Amsterdam, P.O. Box 7057, 1007 MB Amsterdam, the Netherlands; Amsterdam Public Health, Mental Health Programme, Amsterdam, the Netherlands.
Background: Postpartum depression is common and may be linked to antepartum insomnia, a potentially modifiable risk factor. We examine the association between insomnia- and postpartum depression symptoms, considering whether psychiatric vulnerability moderates this link.
Method: Participants completed the Insomnia Severity Index during trimester two and three and the Hospital Anxiety and Depression questionnaire postpartum.
Prog Neuropsychopharmacol Biol Psychiatry
January 2025
Department of Psychotherapy and Psychosomatic Medicine, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany. Electronic address:
Background: After the birth of a child, also fathers may develop postpartum depression. Altered steroid hormone concentrations are discussed as a possible underlying mechanism, as these have been associated with depressive symptoms in previous studies outside the postpartum period. While higher paternal testosterone levels have been found to protect against paternal postpartum depressive symptoms (PPDS), an association between higher cortisol levels and PPDS has been seen in postpartum mothers, with no comparable studies available on fathers.
View Article and Find Full Text PDFPsychoneuroendocrinology
January 2025
Radboud university medical center, Donders Institute for Brain, Cognition and Behaviour, Department of Cognitive Neuroscience, Nijmegen, the Netherlands.
Background: Maternal stress can have short and long term adverse (mental) health effects for the mother and her child. Previous evidence suggests that the gut microbiota may be a potential mediator and moderator for the effects of stress via various pathways. This study explored the maternal microbiota trajectory during pregnancy as well as the association between pre- and postnatal maternal stress and features of the maternal and infant gut microbiota during and after pregnancy.
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