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Palladium-catalysed deaminative/decarboxylative cross-coupling of organoammonium salts with carboxylic acids. | LitMetric

Palladium-catalysed deaminative/decarboxylative cross-coupling of organoammonium salts with carboxylic acids.

Org Biomol Chem

Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Hainan Provincial Key Lab of Fine Chem, Hainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou, 570228, China.

Published: February 2023

A palladium-catalysed carbon-carbon bond-forming reaction deaminative/decarboxylative cross-coupling of organoammonium salts with carboxylic acids was developed. Under the reaction conditions, polyfluoroaromatic carboxylic acids, propiolic acids and α-cyano benzyl carboxylic acid reacted smoothly with benzyl ammonium salts to produce the corresponding carbon-carbon coupling products in good-to-excellent yields.

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Source
http://dx.doi.org/10.1039/d2ob02251fDOI Listing

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