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This paper introduces a comprehensive dataset of spectral-domain optical coherence tomography (SD-OCT) images of human eyes affected by paracentral acute middle maculopathy (PAMM). Acquired with an SD-OCT device (Optovue, Fremont, California, USA), the dataset includes 133 OCT images of lesions. Each image is paired with a corresponding YOLO label in TXT format, representing manually annotated lesion regions of PAMM, created with the assistance of ophthalmologists.

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Purpose: To perform a quantitative multimodal evaluation in 25 patients with primary antiphospholipid syndrome (PAPS) without ocular complaints and to compare them with 25 healthy individuals.

Methods: A structural and functional ophthalmological evaluation using optical coherence tomography angiography (OCTA) and microperimetry (MP) exam in 25 patients with PAPS, followed at a tertiary rheumatology outpatient clinic, was performed. All ophthalmologic manifestations were documented and subsequent statistical analysis was performed for comparative purposes, with significance set at < 0.

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[A case of post-traumatic paracentral acute middle maculopathy associated with glaucoma].

J Fr Ophtalmol

December 2024

Service d'Ophtalmologie III, Centre hospitalier national d'ophtalmologie des Quinze-Vingts, IHU FOReSIGHT, 28, rue de Charenton, 75012 Paris, France; Institut de la vision, Sorbonne université, INSERM, CNRS, IHU FOReSIGHT, 17, rue Moreau, 75012 Paris, France; Hôpital Ambroise-Paré, AP-HP, université de Versailles Saint-Quentin-en-Yvelines, 9, avenue Charles-De-Gaulle, 92100 Boulogne Billancourt, France; Inserm-DGOS, centre d'investigation clinique 1423, Centre hospitalier national d'Ophtalmologie des Quinze-Vingts, IHU FOReSIGHT, 28, rue de Charenton, 75012 Paris, France.

Paracentral acute middle maculopathy is a lesion of the inner nuclear layer and outer plexiform layer of the macula associated with local or systemic vascular diseases that can induce retinal hypoxia. The etiologic mechanism may be related to the increase in intraocular pressure which creates conditions of hypoperfusion in the retinal vasculature. We present a case that shows a possible association between paracentral acute middle maculopathy and glaucoma with the trauma of elevated intraocular pressure as a triggering event.

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Purpose: To determine if paracentral acute middle maculopathy (PAMM) and peripapillary intraretinal and subretinal fluid (IRF/SRF) could help distinguish between arteritic anterior ischemic optic neuropathy (A-AION) and non-arteritic AION (NA-AION) at an early stage.

Design: Nested prospective cross-sectional diagnostic accuracy study.

Methods: This study used single-center optical coherence tomography (OCT) data from 8 patients with A-AION and 24 patients with NA-AION from two prospective cross-sectional studies with consecutive sampling (ClinicalTrials.

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Paracentral acute middle maculopathy (PAMM) is a form of ischaemic maculopathy involving infarction of the inner nuclear layer secondary to deep retinal capillary plexus ischaemia. Risk factors include retinal vascular disease and systemic vascular risk factors, which can predispose the eye to ischaemia. Recent reports now show associations with pregnancy and also migraine episodes.

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