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Adalimumab-induced sensory vasculitic neuropathy.
Drug Ther Bull
September 2023
Department of Neurology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Adalimumab-induced sensory vasculitic neuropathy.
BMJ Case Rep
January 2022
Department of Neurology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Article Synopsis
- Vasculitis and autoimmune conditions can occur as complications from TNF-α inhibitors, leading to varied presentations, including isolated vasculitic neuropathy.
- Diagnosing vasculitic neuropathy is challenging due to the limited sensitivity of peripheral nerve biopsies, making thorough patient history and clinical suspicion essential.
- The text discusses a specific case of sensory vasculitic neuropathy induced by adalimumab, highlighting the treatment approach based on guidelines for non-systemic vasculitic neuropathy.
Mononeuritis multiplex as the first presentation of refractory sarcoidosis responsive to etanercept.
BMC Neurol
December 2014
Queen Mary University London, Blizard Institute, 4 Newark Street, London, E1 1AT, UK.
Background: Several disorders may present with mononeuritis multiplex and the etiological diagnosis can be challenging.
Case Presentation: We report a 42 year-old female who presented with severe lower limb neuropathic pain, asymmetric weakness and sensory impairment and was diagnosed with mononeuritis multiplex. Biopsy showed a granulomatous vasculitic process with eosinophils, scarce granulomata and axonal neuropathy and granulomatosis with poliangiitis was assumed.
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