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Vitamin D: Evidence-Based Health Benefits and Recommendations for Population Guidelines.
Nutrients
January 2025
Orthomolecular Medicine News Service, Columbia, SC 29212, USA.
Vitamin D offers numerous under-recognized health benefits beyond its well-known role in musculoskeletal health. It is vital for extra-renal tissues, prenatal health, brain function, immunity, pregnancy, cancer prevention, and cardiovascular health. Existing guidelines issued by governmental and health organizations are bone-centric and largely overlook the abovementioned extra-skeletal benefits and optimal thresholds for vitamin D.
View Article and Find Full Text PDFInflammatory Markers and Severity in COVID-19 Patients with Clostridioides Difficile Co-Infection: A Retrospective Analysis Including Subgroups with Diabetes, Cancer, and Elderly.
Biomedicines
January 2025
Department I, Discipline of Anatomy and Embryology, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania.
Background And Objectives: The interplay of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection and infection (CDI) poses a critical clinical challenge. The resultant inflammatory milieu and its impact on outcomes remain incompletely understood, especially among vulnerable subgroups such as elderly patients, those with diabetes, and individuals with cancer. This study aimed to characterize inflammatory markers and composite inflammatory severity scores-such as Acute Physiology and Chronic Health Evaluation II (APACHE II), Confusion, Urea, Respiratory rate, Blood pressure, and age ≥ 65 years (CURB-65), National Early Warning Score (NEWS), and the Systemic Immune-Inflammation Index (SII)-in hospitalized Coronavirus Disease 2019 (COVID-19) patients with and without CDI, and to evaluate their prognostic implications across key clinical subgroups.
View Article and Find Full Text PDFAPPLICATION OF IMPROVED AUTODERMOPLASTY TECHNIQUE IN GRANULATING WOUNDS TREATMENT.
Georgian Med News
November 2024
1Department of Hospital Surgery, Anesthesiology and Reanimatology, Non-Commercial Joint-Stock Company "Semey Medical University" (NCJSC "SMU"), Republic of Kazakhstan.
Unlabelled: This prospective study was conducted at the Department of Surgery of the Pavlodar branch of the NCJSC "SMU" (Non-profit joint-stock company "Medical University of Semey" based on the city hospital No. 1, surgical hospital of Pavlodar, Kazakhstan.
Purpose: The purpose of research is to evaluate the results of improved autodermoplasty technique for granulating wounds of different origin.
COST-EFFECTIVENESS OF TREATMENT OF RHEUMATOID ARTHRITIS WITH BIOLOGICAL DRUGS IN GEORGIA.
Georgian Med News
November 2024
Aim: This study aims to assess the cost-effectiveness of treatment with biological drugs-specifically infliximab, adalimumab, and rituximab-both as monotherapy and in combination therapy for patients with rheumatoid arthritis. Additionally, we will identify the factors that influence this process.
Materials And Methods: A total of 60 patients with moderate to severe rheumatoid arthritis (DAS28 > 3.
CLINICAL EFFICACY OF DIFFERENT SURGICAL METHODS IN CONGENITAL PREAURICULAR FISTULA SURGERY.
Georgian Med News
November 2024
Department of Otolaryngology, Jiaozhou Central Hospital of Qingdao, Shandong, China.
Objective: To evaluate the clinical efficacy of different surgical methods in congenital preauricular fistula surgery.
Methods: 60 patients with congenital preauricular fistula were selected and randomly divided into a microscope group of 30 cases and a macroscopic group of 30 cases. The microscope team used the fistula separation method to perform surgery along with the fistula opening.
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