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| http://dx.doi.org/10.1093/plcell/koad004 | DOI Listing |
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Genomic Resources for the Scuttle Fly : A Model Organism for Comparative Developmental Studies in Flies.
bioRxiv
January 2025
University of Chicago, Dept. of Organismal Biology and Anatomy, 1027 East 57 Street, Chicago, Illinois 60637, USA.
The order Diptera (true flies) holds promise as a model taxon in evolutionary developmental biology due to the inclusion of the model organism, , and the ability to cost-effectively rear many species in laboratories. One of them, the scuttle fly (Phoridae) has been used in evolutionary developmental biology for 30 years and is an excellent phylogenetic intermediate between fruit flies and mosquitoes but remains underdeveloped in genomic resources. Here, we present a chromosome-level assembly and annotation of and transcriptomes of 9 embryonic and 4 postembryonic stages.
View Article and Find Full Text PDFMining the secreted and membrane transcriptome of Hyalomma dromedarii ticks for identification of potential protective antigens.
Parasit Vectors
November 2024
Molecular Biology Department, Biotechnology Research Institute, National Research Centre, Cairo, Egypt.
Article Synopsis
- - The study focuses on Hyalomma dromedarii ticks, which are significant for transmitting pathogens to large animals in Egypt, especially as camels and cattle are imported from neighboring countries.
- - Researchers analyzed the transcriptome of these ticks by examining mixed mRNAs from various life stages (eggs, larvae, nymphs, and both fed and unfed adults) to understand the biochemical interactions that take place during tick feeding.
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A tridimensional atlas of the developing human head.
Cell
December 2023
Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France; Institut de pathologie, Groupe Hospitalier Est, Hospices Civils de Lyon, Lyon, France; University Claude Bernard Lyon 1, MeLiS, CNRS UMR 5284, INSERM U1314, 69008 Lyon, France. Electronic address:
The evolution and development of the head have long captivated researchers due to the crucial role of the head as the gateway for sensory stimuli and the intricate structural complexity of the head. Although significant progress has been made in understanding head development in various vertebrate species, our knowledge of early human head ontogeny remains limited. Here, we used advanced whole-mount immunostaining and 3D imaging techniques to generate a comprehensive 3D cellular atlas of human head embryogenesis.
View Article and Find Full Text PDFOpportunities for Bioactive Glass in Gastrointestinal Conditions: A Review of Production Methodologies, Morphology, Composition, and Performance.
Mol Pharm
December 2023
The University of Queensland, School of Pharmacy, The Pharmacy Australia Centre of Excellence, 20 Cornwall St, Woolloongabba, Queensland 4102, Australia.
Bioactive glasses (BGs) are widely used in orthopedic and dental applications for their ability to stimulate endogenous bone formation and regeneration. BG applications more recently broadened to include soft tissue conditions, based on their ability to stimulate angiogenesis, soft tissue regeneration, and wound healing. Sol-gel synthesis has helped facilitate this expansion, allowing formulators to tailor the morphological characteristics of the BG matrix.
View Article and Find Full Text PDFMolecular characterizations and functional roles of NANOG in early development of porcine embryos.
Gene
January 2024
College of Life Science, Northeast Agricultural University, Harbin 150030, China; Key Laboratory of Animal Cellular and Genetic Engineering of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, China. Electronic address:
Nanog homeobox (NANOG) is the gateway to the pluripotent ground state in mouse embryonic stem cells and early embryos. However, understanding of the molecular signatures and functional characteristics of porcine NANOG remains limited. In this study, we analyzed the gene structure and sequence characteristics of porcine NANOG and found that the porcine NANOG gene is localized on chromosome 5, while NANOG sequence on chromosome 1 is the processed pseudogene.
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