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MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration.
Elife
January 2025
Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, Junior Research Group Synthetic Microbiology, Jena, Germany.
Mycofactocin is a redox cofactor essential for the alcohol metabolism of mycobacteria. While the biosynthesis of mycofactocin is well established, the gene , which encodes an oxidoreductase of the glucose-methanol-choline superfamily, remained functionally uncharacterized. Here, we show that MftG enzymes are almost exclusively found in genomes containing mycofactocin biosynthetic genes and are present in 75% of organisms harboring these genes.
View Article and Find Full Text PDFModality-, feature-, and strategy-dependent organization of low-level working memory.
J Vis
January 2025
Department of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany.
Previous research has shown that, when multiple similar items are maintained in working memory, recall precision declines. Less is known about how heterogeneous sets of items across different features within and between modalities impact recall precision. In two experiments, we investigated modality (Experiment 1, n = 79) and feature-specific (Experiment 2, n = 154) load effects on working memory performance.
View Article and Find Full Text PDFPediatric Transplant Surgeons' Perspectives on Palliative Care for Children With Chronic Kidney Disease: A National Cross-Sectional Survey.
Pediatr Transplant
March 2025
Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Background: Some adult transplant surgeons consider transplant to be contraindicated in patients receiving palliative care (PC). Little is known about pediatric transplant surgeons' attitudes toward PC. We sought to ascertain pediatric kidney transplant surgeons' perspectives regarding the routine integration of PC for children with chronic kidney disease.
View Article and Find Full Text PDFAccess to child-appropriate medicines: an exploratory survey of the use of paediatric use marketing authorisation products in the UK.
Eur J Pediatr
January 2025
Pharmacy Department, Guy's and St Thomas' NHS Foundation Trust, Evelina London Children's Hospital, Westminster Bridge Road, London, SE1 7EH, UK.
The Paediatric Use Marketing Authorisation (PUMA) was introduced in the European Union to incentivise the development of off-patent medicines in children. However, there is limited data on the accessibility of PUMA products at the healthcare provider level. This study aimed to identify factors affecting real-world accessibility to PUMA products in the United Kingdom (UK).
View Article and Find Full Text PDFHow is maternal employment associated with infant and young child feeding in Bangladesh? A systematic literature review and meta-analysis.
PLoS One
January 2025
Department of Clinical Sciences, Health Economics Unit, Lund University, Lund, Sweden.
Background: In the last three decades, the increasing trend in female employment in Bangladesh has been critically analyzed from a socioeconomic point of view; however, its impact on infant and young child feeding (IYCF) practices has yet to be systematically reviewed. The aim of this systematic review and meta-analysis is to investigate the association between these variables.
Methods: A systematic literature search was conducted in PubMed, Medline, Web of Science, Embase, CINAHL, and Google Scholar to retrieve relevant records with no restriction of publication period.
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