AI Article Synopsis

  • A 77-year-old woman suffered a massive pulmonary embolism after receiving heparin for DVT prevention following gastric cancer surgery.
  • She was diagnosed with heparin-induced thrombocytopenia post-surgery, confirmed by elevated serum antibodies and low platelet counts.
  • Her treatment was adjusted from intravenous heparin to argatroban, highlighting the need for awareness of this condition in patients with prior heparin use.

Article Abstract

We report a case of a 77-year-old woman with massive pulmonary embolism associated with heparin-induced thrombocytopenia. Before developing a pulmonary embolism, the patient underwent gastrectomy due to gastric cancer and received subcutaneous heparin calcium for deep venous thrombosis prophylaxis for 5 d. Then, thrombectomy with cardiopulmonary bypass using full heparinization was successfully performed. The patient was definitively diagnosed with this condition postoperatively, based on elevated serum antibody levels, in addition to pre- and postoperative thrombocytopenia and thrombosis. Intravenous heparin therapy was switched to argatroban. Although it is uncommon, clinicians should consider this condition in patients with a history of heparin exposure.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816026PMC
http://dx.doi.org/10.3400/avd.cr.22-00082DOI Listing

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