In this study, we present the case of a 10-year-old boy with a left-sided neck mass. Although most neck masses in children are non-cancerous, their etiology can be complex, especially in neck masses of congenital origin. The workup of a pediatric neck mass includes imaging and cytopathology. In this case, the histopathology of the excised mass revealed thymic tissue, which helped establish the diagnosis of a thymopharyngeal duct cyst. Thymophayngeal duct cysts, although rare, can be diagnosed preoperatively by characteristic tapering toward the mediastinum. Cytopathology may demonstrate Hassall corpuscles. These unique features can help disentangle the differential diagnoses, which commonly include thyroglossal duct cysts, venolymphatic malformations, and branchial cleft cysts.
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http://dx.doi.org/10.7759/cureus.32468 | DOI Listing |
Hear Res
December 2022
Eaton-Peabody Lab, Mass. Eye and Ear, 243 Charles St., Boston MA 02114, USA.
Many details of the operation of the mammalian cochlea are known, but how they all work together to produce cochlear amplification is not understood. Outer-hair-cell (OHC) motility produces two kinds of amplification: non-propagating amplification (NPA) that is from local OHCs, and traveling-wave amplification (TWA) that increases basilar-membrane (BM) motion. Proposed here are a series of hypotheses that provide a new explanation, the "OoC-area-pump", for TWA: (1) In the short-wave region OHC vibrations cause cyclic longitudinal motion of fluid in the organ of Corti (OoC) and peri-Deiters-cell tissue, (2) the longitudinal motion changes the local OoC area, which (3) by reticular-lamina (RL) movement drives the fluid in scala media in a way that amplifies the fluid-pressure traveling wave.
View Article and Find Full Text PDFInt Forum Allergy Rhinol
January 2025
Department of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, USA.
Background: We developed and assessed the performance of a machine learning model (MLM) to identify, classify, and segment sinonasal masses based on endoscopic appearance.
Methods: A convolutional neural network-based model was constructed from nasal endoscopy images from patients evaluated at an otolaryngology center between 2013 and 2024. Images were classified into four groups: normal endoscopy, nasal polyps, benign, and malignant tumors.
Ulus Travma Acil Cerrahi Derg
January 2025
Department of Biochemistry, Gulhane Faculty of Pharmacy, University of Health Sciences, Ankara-Türkiye.
Background: Osteoporosis is characteristically defined as a decrease in bone density and mass, accompanied by the deterioration of bone structure, which increases bone fragility and the risk of fractures. Osteoporosis frequently develops with age. In high-risk populations, oxidative damage is a common pathological condition.
View Article and Find Full Text PDFHead Neck Pathol
January 2025
Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School, Boston, MA, USA.
We present the case of a 51-year-old man with Von Hippel-Lindau disease and a history of renal transplantation who developed a persistent, painful tongue lesion with episodes of significant swelling. Given his history of prolonged immunosuppression and elevated cancer risk, oral squamous cell carcinoma was a major concern. However, histopathological evaluation confirmed recrudescent herpes simplex virus (HSV) infection rather than malignancy.
View Article and Find Full Text PDFThis study investigates the impact of the weight and centre of mass (COM) position of Head-Mounted Displays (HMDs) on the subjective evaluation of users during prolonged wearing tasks. This study involved 88 participants completing 1860 sets of experiments under three conditions: sitting still, turning the head, and moving, providing subjective evaluations of wearing HMDs. A static torque testing device was used to simulate neck torque under flexion states.
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