The Schiff bases were prepared with aromatic aldehyde and aromatic amine using cashew shell extract as a catalyst under microwave irradiation. This reaction is rapid, efficient, and solvent-free and involves the one-pot synthesis of Schiff bases under microwave irradiation. The synthesized Schiff bases were characterized by Fourier transform infrared (FTIR) spectroscopy, H nuclear magnetic resonance (NMR) spectroscopy, C NMR spectroscopy, and gas chromatography-mass spectrometry (GC-MS). The advantages of the preparation of Schiff bases under microwave irradiation are high yield, shorter reaction time, easy, elimination of side products, and quick product isolation. The synthesized Schiff base derivatives are well known for their biological activity like antibacterial and antifungal activity.
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http://dx.doi.org/10.1021/acsomega.2c05187 | DOI Listing |
Dalton Trans
January 2025
Departamento de Química Inorgánica, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
The aza-Wittig reaction was successfully applied to the synthesis of carboranyl-imines, which are difficult to obtain by classical methods. A variety of functionalized carboranyl Schiff bases was obtained proving the great scope of the methodology. All compounds were fully characterized, including the solid-state structures of six of them.
View Article and Find Full Text PDFMini Rev Med Chem
January 2025
Department of Chemistry, Abdul Wali Khan University, Mardan, 23200, Pakistan.
Organic compounds containing azines, di-imines, or bis-Schiff-bases have two azomethine (-CH=N-) functional groups associated with a bridging component. These constituents have attracted attention from a diversity of disciplines, comprising coordination, medicinal, agriculture chemistry, and organic synthesis, because of their comprehensive chemical reactivity and nature. This study determines common synthetic approaches and various biological and pharmacological activities of several substituted bis-Schiff byproducts.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Department of Chemistry, Faculty of Science, Arak University, Arak 38481-77584, Iran; Institute of Nanosciences &Nanotechnology, Arak University, Arak, Iran. Electronic address:
The rapid industrialization and human activities in catchments have posed notable global challenges in removing of heavy metal contaminants from wastewater. Here, Schiff-bases (SB) of cyanoguanidine (CG) and salicylaldehyde (SA) were covalently grafted on a magnetic nanocomposite of chitosan to form a hybrid magnetic nanostructure (FeO@CS-CGSB). The synthesized structure was characterized using various techniques such as Fourier transform infrared spectroscopy (FT-IR), field emission scanning electron microscopy (SEM), transmission electron microscopy (TEM), powder X-ray diffraction (XRD), thermogravimetric analysis (TGA), vibrating sample magnetometry (VSM), dynamic light scattering (DLS), zeta potential, and Brunauer-Emmett-Teller surface area analysis (BET).
View Article and Find Full Text PDFFood Chem
January 2025
College of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China. Electronic address:
Herein, we developed multifunctional hydrogels formed between soybean protein (SPI)-gallic acid conjugate and oxidized dextran (ODex) via a Schiff base reaction. The effects of ODex on the morphology, structure, and functional properties of the hydrogels were elucidated. The results showed that the crosslinking modes in the hydrogels include hydrogen bonding, Schiff bases, Michael addition, and π-π stacking.
View Article and Find Full Text PDFRSC Med Chem
December 2024
Department of Pharmaceutical Chemistry, College of Pharmacy, The University of Mashreq Baghdad 10023 Iraq.
Many cancers have displayed resistance to chemotherapeutic drugs over the past few decades. EGFR has emerged as a leading target for cancer therapy inhibiting tumor angiogenesis. Besides, studies strongly suggest that blocking telomerase activity could be an effective way to control the growth of certain cancer cells.
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