Electrically induced anisotropic assembly of chitosan with different molecular weights.

Anisotropic hydrogel is emerging as an important soft matter in the field of bionics and bioactuators, owing to its outstanding mechanical toughness and strength. Understanding the dynamic construction process of anisotropic hydrogel is beneficial for matching subsequent application. In this work, we establish an electrical field in microfluidics for the in-situ real time visualization of anisotropic assembly of chitosan, an amino polysaccharide. Polarized light microscopy is adopted to observe the dynamic growth of chitosan with different molecular weights. The results demonstrate that electrical signal has a profound influence on anisotropic assembly process of chitosan. It is interesting to notice that high oriented structure can be found in chitosan hydrogel with large molecular weight, which exhibits a dense and compact structure. This work provides a new perspective for predicting and controlling the formation of different molecular weights anisotropic chitosan hydrogels, which permit the rational design of chitosan hydrogels with excellent mechanical properties and specific functions.