A sonochemical based green synthesis method playa powerful role in nanomaterials and composite development. In this work, we developed a perovskite type of strontium titanate via sonochemical process. SrTiO particles were incorporated with nitrogen doped graphene oxide through simple ultrasonic irradiation method. The SrTiO/NGO was characterized by various analytical methods. The nanocomposite of SrTiO/NGO was modified with laser-induced graphene electrode (LIGE). The SrTiO/NGO/LIGE was applied for electrochemical sensor towards chemotherapeutic drug detection (nilutamide). Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques have been used to examine the electrochemical performance of nilutamide (anti-cancer drug). DPV was found to be more sensitive and found to exhibit a sensitivity 8.627 µA µM cm for SrTiO/NGO/LIGE with a wide linear range (0.02-892 µM) and low Limit of detection (LOD: 1.16 µM). SrTiO/NGO/LIGE has been examined for the detection of nilutamide in blood serum and urine samples and obtained a good recovery in the range of 97.2-99.72 %. The enhanced stability and selectivity and practical application results indicates the suitability of SrTiO/NGO/LIGE towards the detection of nilutamide drug in pharmaceutical industries.
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| http://dx.doi.org/10.1016/j.ultsonch.2023.106293 | DOI Listing |
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