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| http://dx.doi.org/10.5009/gnl220533 | DOI Listing |
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Background: this investigation aimed to assess the correlation between the triglyceride glucose (TyG) index and its related indicators, as well as the ratio of triglyceride to high-density lipoprotein cholesterol (TG/HDL-c), with hepatic steatosis and liver fibrosis among middle-aged and elderly participants.
Methods: based on data from the 2017-2020 National Health and Nutrition Examination Survey, the study included adults of ages 40 years and older in the United States. To explore the correlation between TyG and its related indicators, as well as TG/HDL-c with hepatic steatosis and liver fibrosis, multiple regression models were employed.
Metabolic pathways to sustainability: review of purple non-sulfur bacteria potential in agri-food waste valorization.
Front Bioeng Biotechnol
February 2025
Laboratory of Proteomics and Microbiology, Research Institute for Biosciences, University of Mons, Mons, Belgium.
Agri-food waste (AFW) represents a significant fraction of the material generated by the agri-food industry, which itself accounts for almost one-third of the annual global anthropogenic greenhouse gas (GHG) emissions. Considering the growing global population and the consequent rise in food demand, the management and valorization of this waste are essential to ensure the sustainability of the entire food chain for future generations. Recycling agri-food waste offers a promising strategy to mitigate the sector's environmental impact, particularly when the waste consists of food-grade materials that enhance its intrinsic value.
View Article and Find Full Text PDFDifferential effects of high-fat diet on salivary and gut microbiota.
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Department of Orthodontics, Peking University School and Hospital of Stomatology, Beijing, China.
Objectives: Microorganisms contribute to the pathogenesis of obesity, while more studies focus on gut microbiome. However, the relationship between oral microbiota and obesity has yet to be elucidated. This study was designed to investigate the similarities and differences in the effects of a high-fat diet on salivary and gut microbiota through mouse experiments, exploring the hypothesis that oral microbial mechanisms may contribute to obesity.
View Article and Find Full Text PDFOptimizing Hepatocellular Carcinoma Screening: A Comparative Simulated Abbreviated MRI Protocol Study.
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Department of Radiology, Krishna Institute of Medical Sciences, Secunderabad, IND.
Background Patients with risk factors such as viral hepatitis-induced liver cirrhosis, advanced-stage primary biliary cirrhosis, hereditary hemochromatosis, metabolic-associated fatty liver disease, and alcoholic liver disease are more likely to develop hepatocellular carcinoma (HCC). Most HCC patients have advanced-stage disease unresponsive to treatment. Therefore, avoiding or treating viral infections and early detection through routine surveillance, such as repeated liver ultrasonography, are the most effective ways to reduce HCC-related mortality.
View Article and Find Full Text PDFMolecular Classification of Hepatocellular Carcinoma based on Zoned Metabolic Feature and Oncogenic Signaling Pathway.
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Department of Gastroenterology and Hepatology/Kindai University Faculty of Medicine, Osaka-Sayama, Japan.
Background/aims: Previously, we advocated the importance of classifying hepatocellular carcinoma (HCC) based on physiological functions. This study aims to classify HCC by focusing on liver-intrinsic metabolism and glycolytic pathway in cancer cells.
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