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Herpes Simplex Virus Infection in Neonates Born to Asymptomatic Mothers: A Case Series. | LitMetric

Herpes Simplex Virus Infection in Neonates Born to Asymptomatic Mothers: A Case Series.

Cureus

Servicio de Dermatología. Alicante Institute for Health and Biomedical Research (ISABIAL), Hospital General Universitario de Alicante, Alicante, ESP.

Published: December 2022

AI Article Synopsis

  • Neonatal herpes is typically acquired during childbirth from mothers who usually show no symptoms, leading to serious risks if not diagnosed and treated quickly.
  • Five cases of neonatal herpes were examined, involving mostly girls, with a majority of the infants being preterm and having complications related to herpes simplex virus (HSV) type 2.
  • Dermatologists play a critical role in the early diagnosis of these cases, highlighting a need for better prevention strategies since no vaccine or inexpensive screening method exists for asymptomatic mothers.

Article Abstract

Neonatal herpes is a rare condition and it is normally acquired through vertical transmission in the peripartum period. Delayed diagnosis and treatment of this condition are associated with high morbidity and mortality. We present five cases of neonatal herpes in infants born to asymptomatic mothers. Three of these infants were girls, three were born preterm, three were born after prolonged rupture of membranes, three had herpes simplex virus (HSV) type 2, and one had central nervous system (CNS) involvement. In all cases, the dermatologist played a key role in establishing an early diagnosis. Given the absence of a vaccine or a cost-effective method of screening for HSV infection in asymptomatic mothers, the current management strategies focus on the prevention of maternal infection and mother-to-child transmission, as well as early diagnosis and treatment of neonatal infection.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830649PMC
http://dx.doi.org/10.7759/cureus.32393DOI Listing

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