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The Role of Single-Cell Profiling and Deep Immunophenotyping in Understanding Immune Therapy Cardiotoxicity. | LitMetric

AI Article Synopsis

  • - ICIs (Immune Checkpoint Inhibitors) in cancer treatment may lead to severe heart-related immune side effects.
  • - Single-cell multi-omics are advanced methods that help identify and analyze different types of cells.
  • - Utilizing multi-omics technology can reveal how ICI-induced myocarditis occurs and its underlying mechanisms.

Article Abstract

• ICIs used in cancer therapy can cause serious cardiac immune-related side effects. • Single-cell multi-omics are powerful tools in understanding cell subsets/phenotypes. • Multi-omics technology can elucidate disease mechanisms in ICI-induced myocarditis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830194PMC
http://dx.doi.org/10.1016/j.jaccao.2022.08.012DOI Listing

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