AI Article Synopsis
- Previous studies indicate that having multiple health issues, like type 2 diabetes (T2DM) and hypertension (HT), increases the risk of cognitive dysfunction (CD), especially in low and middle-income countries.
- The study aimed to explore the link between having both T2DM and HT and cognitive decline in adults aged 50 and older in Tumbes.
- Results showed a significant connection between multimorbidity and cognitive dysfunction, particularly in individuals with 7 or more years of education, highlighting education as a factor that influences this relationship.
Article Abstract
Background: Previous studies have shown that multimorbidity is a risk factor for cognitive dysfunction (CD).Type 2 diabetes mellitus (T2DM) and hypertension (HT) are very common risk factors.The association between multimorbidity due to both diseases and CD has been understudied in low and middle-income countries, in which the strength of the association might be stronger.
Aim: To evaluate the association between multimorbidity due to T2DM and HT with CD among adults ≥50 years in Tumbes.
Materials And Methods: A secondary analysis of a population-based cross-sectional study was conducted. The exposure variable was the presence of both T2DM and HT, split into categories: without HT or T2DM, only T2DM, only HT, and with T2DM and HT; whereas CD was the outcome variable, defined as a score ≤26 in the Leganes Cognitive Test. Crude and adjusted generalized linear models were used to estimate the association of interest, and prevalence ratio (PR) and 95% confidence interval (95%CI) were reported.
Results: 688 participants were analyzed. The prevalence of CD was 39.1%. There was a 56.1% of participants without TDM2 nor HT, 8.3% with T2DM, 28.9% with HT and 6.7% with both diseases. A significant association was found between multimorbidity and CD (PR = 1.43, 95%CI 1.04-1.97). Multimorbidity had a statistically significant association with CD in the group of participants with ≥7 years of education (PR = 2.56,95%CI 1.55-4.21), but no in the group with <7 years.
Conclusions: There is association between the morbidity of T2DM and HT, and CD among adults ≥50 years of age in Tumbes. Education was an effect modifier of the association between HT and T2DM on the presence of CD.
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| http://dx.doi.org/10.1016/j.jns.2023.120543 | DOI Listing |
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