Background/aim: Pancreatic head adenocarcinoma represents the most aggressive digestive malignancy, which affects patients worldwide and is associated with poor outcomes especially due to the fact that most cases are diagnosed when local vascular invasion is already present.

Case Report: This is a case report of a 44-year-old patient diagnosed with a borderline resectable pancreatic head adenocarcinoma invading the superior mesenteric artery. The patient was submitted to surgery, and intraoperatively the mesenteric artery invasion was found. A pancreatoduodenectomy en bloc with superior mesenteric artery resection was performed while the continuity of the arterial structure was re-established by placing a cadaveric graft.

Conclusion: In selected cases, extended arterial resections might be needed in order to achieve negative resection margins and therefore, to improve the chances of long-term survival.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801448PMC
http://dx.doi.org/10.21873/cdp.10191DOI Listing

Publication Analysis

Top Keywords

mesenteric artery
16
superior mesenteric
12
pancreatoduodenectomy bloc
8
bloc superior
8
artery resection
8
borderline resectable
8
resectable pancreatic
8
case report
8
pancreatic head
8
head adenocarcinoma
8

Similar Publications

Purpose: Mesenteric artery embolism (MAE) is a relatively uncommon abdominal surgical emergency, but it can lead to catastrophic clinical outcomes if the diagnosis is delayed. This study aims to build a prediction model of clinical-radiomics nomogram for early diagnosis of MAE based on non-contrast computed tomography (CT) and biomarkers.

Method: In this retrospective study, a total of 364 patients confirmed as MAE (n = 131) or non-MAE (n = 233) who were randomly divided into a training cohort (70%) and a validation cohort (30%).

View Article and Find Full Text PDF

Background: The quality of life after surgery for diverticular disease is mainly linked to the presence and severity of postoperative defecatory disorders. These symptoms are frequently related to the sigmoid and rectal denervation following the arterial ligation. The preservation of Inferior Mesenteric Artery performing colorectal resections seems to reduce denervation, which led to a better defecatory function.

View Article and Find Full Text PDF

Superior mesenteric artery syndrome in a pediatric patient: A rare case report and literature review.

Int J Surg Case Rep

January 2025

General Surgery Department, Military Hospital of Tunis, Mont Fleury, 1008 Tunis, Tunisia; Faculty of Medicine of Tunis, 15, Djebel Lakhdhar Street, Bab Saadoun, 1007 Tunis, Tunisia.

Introduction And Importance: Superior mesenteric artery (SMA) syndrome, or aorto-mesenteric clamp syndrome, is a rare condition where the third portion of the duodenum is compressed between the aorta and the superior mesenteric artery. This syndrome often affects adolescents and young adults, with predisposing factors including significant weight loss, anatomical variations, and spinal deformities. Early diagnosis and intervention are critical for managing symptoms and preventing complications.

View Article and Find Full Text PDF

A 55-year-old woman with non-small cell lung carcinoma complained of epigastric pain, bloating, anorexia and postprandial nausea and vomiting over a five-year period. An upper gastrointestinal pan-glucosamine contrast examination revealed a distinctive large, hook-shaped, ptotic gastric lumen with normal motility. The contrast agent demonstrated an abnormal round-trip flow anterior to the spine at the duodenal level, with pooling and gradual passage through this region in strands after prolonged retention.

View Article and Find Full Text PDF

The pan-PPAR agonist lanifibranor reduces portal pressure independent of fibrosis reduction through the splanchnic vasculature.

Biomed Pharmacother

January 2025

Department of Internal Medicine and Pediatrics, Hepatology Research Unit, Ghent University, Ghent, Belgium; Liver Research Center Ghent, Ghent University, Ghent University Hospital, Ghent, Belgium. Electronic address:

Portal hypertension (PH) can cause severe complications in patients with advanced chronic liver disease (aCLD). The pan-peroxisome proliferator-activated receptor (pan-PPAR) agonist lanifibranor reduces portal pressure in preclinical models of aCLD. Since the effect on PH might be secondary to fibrosis improvement, we investigated the effect of lanifibranor on PH, hepatic and splanchnic angiogenesis in mouse models of fibrotic and prehepatic non-fibrotic PH.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!