Microchannels fabricated by femtosecond laser-assisted chemical etching are of great use in biochemical analysis. In this paper, we study the morphology change of etched microchannels in fused silica by controlling the laser scan speed, and we find a significant difference between the chemical etched length and volume. The fabricated microchannels would gradually become tapered along the scan direction, which influences the flow of the hydrofluoric (HF) reagent and the etching rate. As a result, the difference ratios of the etched length and volume, respectively, reach -5.56 and -41.83 followed by the scan speed increasing from 5 to 200 µm/s. Microchannels with polarization independence and better aspect ratio could be obtained in a high-speed-scan mode. We suggest that laser-induced structural transformation from interconnected microcracks to nanogratings could be responsible for this change. Aforementioned results offer a feasible approach to achieve polarization-independent microchannels, which is in favor of accelerating the fabrication of three-dimensional microfluidic devices.
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http://dx.doi.org/10.1364/AO.475940 | DOI Listing |
Invest Ophthalmol Vis Sci
January 2025
Singapore Eye Research Institute, Singapore.
Purpose: To investigate the aqueous proteomics and metabolomics in low-energy and high-energy femtosecond laser-assisted cataract surgery (FLACS).
Methods: In this prospective observational study, 72 patients were randomized to 3 groups: low-energy FLACS, high-energy FLACS, and conventional phacoemulsification (controls). Aqueous was collected after femtosecond laser treatment or at the beginning of surgery (controls).
Sci Rep
January 2025
Department of Ophthalmology, Parkway Gleneagles Medical and Surgical Center, 389 Nanjing Xi Rd, Shanghai, 200032, China.
This study aims to compare the efficacy and safety of femtosecond laser-assisted implantable collamer lens (ICL) implantation with traditional manual ICL techniques. A retrospective analysis was conducted on patients who underwent ICL implantation at Beijing New Vision Eye Hospital in 2023. Patients (aged 18-45) were matched for gender and refractive error, with forty-two eyes in each group.
View Article and Find Full Text PDFBioengineering (Basel)
November 2024
Singapore National Eye Center, Singapore 168751, Singapore.
We describe retrospectively the indications and outcomes of nine patients who present with varying degrees of deep posterior stromal scarring or endothelial failure following deep anterior lamellar keratoplasty (DALK). These patients underwent a surgical strategy coined Intraoperative Optical Coherence Tomography Guided Femtosecond Laser-Assisted Descemet Membrane Endothelial Keratoplasty (iFAD). This strategy can be used to address suboptimal visual outcomes following primary DALK.
View Article and Find Full Text PDFBMC Ophthalmol
December 2024
School of Medicine, Xiamen Eye Center and Eye Institute of Xiamen University, Xiamen, 361000, China.
Purepose: The intraoperative femtosecond laser time, Cumulative Dissipated Energy (CDE), Effective Phacoemulsification time (EPT), and intraoperative fluid perfusion volume were compared under different model fragmentation modes using Catalys femtosecond laser system.
Methods: This was a single-center, prospective, randomized controlled study. A total of 120 eyes who underwent femtosecond laser-assisted cataract phacoemulsification combined with intraocular lens implantation in Xiamen Eye Center affiliated to Xiamen University from September 2022 to March 2023 were randomly divided into 4 groups to undergo pre-nucleus splitting in different ways: Group 1: six-split, Group 2: eight-split, Group 3: six-split + gridded softening, and Group 4: eight-split + gridded softening.
J Cataract Refract Surg
December 2024
Department of Ophthalmology, Sorocaba Eye Hospital, Sorocaba Eye Bank, Sorocaba, São Paulo, Brazil.
Purpose: To investigate the effectiveness and safety of customized femtosecond laser-assisted corneal allogenic intrastromal ring segments (CAIRS) implantation in keratoconus patients with a history of intrastromal corneal ring segment (ICRS) explantation.
Setting: Sorocaba Eye Hospital (Hospital Oftalmológico de Sorocaba - HOS), Sorocaba, Brazil.
Design: Prospective case series.
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