Objective: This study was conducted to ascertain the long-term complications of chronic traumatic paraplegia and the quality of life of paraplegic patients. Study Design: A retrospective descriptive study.
Place And Duration Of Study: Conducted at Fauji Foundation Hospital, Rawalpindi, Pakistan.
Materials And Methods: Twenty-six admitted male patients suffering from traumatic paraplegia were physically and neurologically examined, and the available laboratory and radiological investigations were done. The medical records of all patients were thoroughly reviewed.
Results: Falls were found to be the most common cause of the paraplegia (57.7%). Neurological recovery did not occur in any patient, even after three decades. All patients had developed complications of urinary tract infections, such as chronic renal failure, renal/ bladder stones, and epidydimo-orchitis. Urinalysis showed asymptomatic bacteriuria in all patients. Urine culture showed Pseudomonas Aeruginosa in 65.3% and E. Coli in 42.3% of samples. Multiple uropathogens were present in 77.9% of cases. Persistent and recurrent bed sores were present in 46.1% patients. Many patients had episodic, burning leg pain, spasticity of legs (76.9%), and contractures of knee joints. All patients were irritable, depressed, and had suicidal ideas.
Conclusions: This study showed that traumatic paraplegia is a permanent disability. It is associated with high morbidity rate due to scores of complications, particularly recurrent urinary tract infections and pressure sores. Prevention, early detection, and timely intervention of potential complications are of the utmost importance.
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http://dx.doi.org/10.7759/cureus.116 | DOI Listing |
Curr Pain Headache Rep
January 2025
Department of Anesthesiology, Advocate Illinois Masonic Medical Center, Chicago, IL, 60657, USA.
Purpose Of The Review: In the United States, spinal cord injuries affect approximately 18,000 individuals annually, most commonly resulting from mechanical trauma. The consequent paraplegia severely impairs motor functions, creating an urgent need for innovative therapeutic strategies that extend beyond traditional rehabilitation and pharmacotherapy. This review assesses the effectiveness of Spinal Cord Stimulation (SCS) in improving motor function in patients with spinal cord injuries, with a particular focus on paraplegia.
View Article and Find Full Text PDFDermatol Ther (Heidelb)
January 2025
Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Dermatology, University of Messina, 98125, Messina, Italy.
Introduction: Patients with psoriasis (PsO) and permanent spinal cord injuries (SCI) resulting in paraplegia and tetraplegia may experience a higher rate of infections compared to patients with PsO without SCI. It can result in further challenges for therapeutic management with immunosuppressants (biological and non-biological treatments). Thus, we aimed to evaluate the rate of infections in patients with PsO and SCI treated with systemic immunosuppressants.
View Article and Find Full Text PDFLancet Neurol
January 2025
Spinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Background: Spinal cord injury results in permanent neurological impairment and disability due to the absence of spontaneous regeneration. NG101, a recombinant human antibody, neutralises the neurite growth-inhibiting protein Nogo-A, promoting neural repair and motor recovery in animal models of spinal cord injury. We aimed to evaluate the efficacy of intrathecal NG101 on recovery in patients with acute cervical traumatic spinal cord injury.
View Article and Find Full Text PDFJ Vasc Surg
December 2024
Department of Cardiothoracic and Vascular Surgery, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, TX.
Objective: The thoracic branch endoprosthesis (TBE) (W.L. Gore) offers an off-the-shelf single option for thoracic endovascular aortic repair (TEVAR) of aortic arch pathology with sealing in zones 0 to 2.
View Article and Find Full Text PDFJ Spinal Cord Med
December 2024
Veterans Health Administration, United States Department of Veterans Affairs, Spinal Cord Injuries & Disorders National Program Office (11SCID), Washington, District of Columbia, USA.
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