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High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar. | LitMetric

AI Article Synopsis

  • Colorectal cancer is widespread globally, with reduced mortality linked to screening; Qatar launched a national screening program in 2016.
  • Fecal immunochemical testing (FIT) was used for individuals aged 50-74, leading to colonoscopies for those who tested positive.
  • Out of 32,751 invitees, 11,130 participated, with 6% testing positive; colonoscopies revealed significant adenoma and cancer detection rates, supporting the need for ongoing, organized screening efforts.

Article Abstract

Introduction: Colorectal cancer is one of the most common cancers globally. Recent reductions in mortality rates have been primarily attributed to screening programs. The State of Qatar established a national bowel cancer screening program in 2016.

Methodology: Fecal immunochemical testing (FIT) was used for average-risk individuals aged 50 to 74 years. Fecal immunochemical testing -positive participants were referred for total colonoscopy to detect polyps and cancers.

Results: Among 32,751 FIT invitees, 11,130 took the test, and 758 (6%) of those were FIT positive. Of these, 375 (56.13%) participants underwent a colonoscopy, and polyps were detected in 198 (52.8%) and cancers in 19 (5.1%) participants. The adenoma detection rate exceeded 40%.

Discussion And Conclusion: The high yield of polyps and cancers in the screening program justifies an active, resource-intensive, and organized bowel cancer screening effort. The high adenoma detection rate in a FIT-based program warrants recalibration of target adenoma detection rates in screening programs.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822526PMC
http://dx.doi.org/10.7759/cureus.32274DOI Listing

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