Objective: To develop a realistic simulation model for laparotomy-assisted fetoscopic spina bifida aperta (SBa) surgery, to be used for training purposes and preoperative planning.
Methods: The predefined general requirement was a realistic model of an exteriorized uterus, allowing all neurosurgical steps of the intervention. The uterus was modelled using ultrasound and MRI images of a 25 weeks' gravid uterus, consisting of flexible polyurethane foam coated with pigmented silicone. The fetal model, contained an opening on the dorsal side for a customizable spinal insert with all the aspects of a SBa, including a cele, placode, and myofascial and skin layer. The model was assessed in a series of validation experiments.
Results: Production costs are low, uterus and fetus are reusable. Placental localization and the level and size of the spinal defect are adjustable, enabling case-specific adaptations. All aspects of the simulator were scored close to realistic or higher for both appearance and functional capacities.
Conclusions: This innovative model provides an excellent training opportunity for centers that are starting a fetoscopic SBa repair program. It is the first simulation model with adjustable spinal defect and placental localisation. Further objective validation is required, but the potential for using this model in preoperative planning is promising.
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http://dx.doi.org/10.1002/pd.6308 | DOI Listing |
3D Print Med
January 2025
Department of Surgical & Interventional Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Background: Penile implant surgery is the standard surgical treatment for end-stage erectile dysfunction. However, the growing complexity of modern high-tech penile prostheses has increased the demand for more practical training opportunities. The most advanced contemporary training methods involve simulation training using cadavers, with costs exceeding $5,000 per cadaver, inclusive of biohazard fees.
View Article and Find Full Text PDFJ Mol Model
January 2025
School of Chemical and Environmental Engineering, China University of Mining and Technology-Beijing, Haidian District, Ding No.11 Xueyuan Road, Beijing, 100083, People's Republic of China.
Context: Understanding the structural characteristics of coal at the molecular level is fundamental for its effective utilization. To explore the molecular structure characteristic, the long-flame coal from Daliuta (DLT), coking coal from Yaoqiao (YQ), and anthracite from Taixi (TX) were investigated using various techniques such as elemental analysis, Fourier transform infrared spectroscopy, solid-state C nuclear magnetic resonance spectroscopy, and X-ray photoelectron spectroscopy. Based on the structural parameters, the coal molecular model was constructed and optimized.
View Article and Find Full Text PDFJ Mol Model
January 2025
College of Electronics and Information, Xi'an Polytechnic University, Xian, People's Republic of China.
Context: The two-dimensional graphene/MoTe heterostructure holds extensive potential applications in optoelectronic devices, sensors, and catalysts. To expand its optical applications, this study systematically investigates the adsorption stability of metal atoms (Au, Pt, Pd, and Fe) on the graphene/MoTe and their influence on its optoelectronic properties employing first-principles methods. The findings indicate that after the adsorption of Au and Pd, the structure retains its direct bandgap properties, while the adsorption of Pt and Fe exhibits indirect bandgap characteristics.
View Article and Find Full Text PDFTraffic Inj Prev
January 2025
China Merchants Chongqing Communications Technology Research & Design Institute Co., Ltd, Chongqing, China.
Objective: This study aimed to analyze the influence of different tunnel reinforcement measures on drivers and to evaluate the associated driving safety risks.
Methods: Experimental data of driving behavior and physiological response were collected under different driving simulation scenarios, such as cover arch erection, corrugated steel, grouting, Steel strips, and fire; an evaluation index system was established based on electrocardiographic (ECG), electrodermal activity(EDA), standard deviation of speed (SDSP), Steering Entropy(SE), standard deviation of lateral position (SDLP) and other indices. The classical domain rank standard of each evaluation index was divided using K-Means algorithm, and a synthetic evaluation matter-element model was established to comprehensively evaluate and analyze the safety risks of each scenario.
Mater Horiz
January 2025
Natural Sciences and Science Education, National Institute of Education, Nanyang Technological University, Singapore 637616, Singapore.
Bionic evaporators inspired by natural plants like bamboo and mushrooms have emerged as efficient generators through water capillary evaporation. However, primitive natural evaporators cannot currently meet growing demand, and their performance limitations remain largely unexplored, presenting a substantial challenge. Through extensive experimentation and detailed simulation analysis, this study presents a precisely engineered H-type bamboo steam generator.
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