An unusual case of multiple myeloma is presented in which recurrence of the disease after a four-year remission was heralded by an infiltrating plasmacytoma of the breast. The clinical and histologic features of this neoplasm are presented and compared with ten previously reported cases of plasmacytoma of the breast.
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Eur J Breast Health
January 2025
Department of Pathology, University of Sousse Faculty of Medicine of Sousse, Farhat Hached Teaching Hospital, Sousse, Tunisia.
Tuberculosis (TB) of the rib is an uncommon manifestation of extrapulmonary TB that can pose significant diagnostic challenges, especially when presenting as a breast mass. We report the case of a 74-year-old woman who presented with a left breast lump, initially suspected to be a plasmacytoma due to its imaging characteristics and clinical history. The mass was surgically excised, and histopathological analysis revealed granulomatous inflammation with caseous necrosis, suggesting TB.
View Article and Find Full Text PDFCureus
October 2024
Internal Medicine, Campbell University School of Osteopathic Medicine, Lillington, USA.
Int J Surg Case Rep
December 2024
Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India. Electronic address:
Introduction And Importance: Solitary plasmacytoma of the breast is an extremely rare manifestation of plasma cell neoplasms, predominantly seen in the bone marrow and commonly associated with multiple myeloma. When it occurs as an isolated lesion in the breast, it presents unique diagnostic and therapeutic challenges due to its rarity and clinical similarity to other breast conditions.
Case Presentation: We report a case of a 60-year-old female presenting with a gradually enlarging mass in her right breast over six months.
Cureus
October 2024
Radiology, King Hamad University Hospital, Muharraq, BHR.
Breast plasmacytoma is an uncommon extramedullary manifestation of multiple myeloma (MM). This case presents a primary extramedullary plasmacytoma and progression to MM with breast involvement after 12 years of discovering the disease. The patient is a 54-year-old woman who initially presented with a right humerus pathological fracture that turned out to be a primary extramedullary plasmacytoma.
View Article and Find Full Text PDFDiagnostics (Basel)
August 2024
Department of Radiology, General University of Patras, 61000 Patras, Greece.
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