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Regulates the Immune Response and Gut Microbiota in Mice.
Nutrients
December 2024
Department of Health and Sports Science, Kawasaki University of Medical Welfare, Kurashiki 701-0193, Japan.
Background: Cactus contains dietary fiber and minerals and is expected to have preventive effects against diabetes, arteriosclerosis, and other diseases. Additionally, cactus intake induces the production of short-chain fatty acids derived from the gut microbiota, which might influence immune functions. In this study, we examined the effects of a cactus (: NC)-supplemented diet on lipopolysaccharide (LPS)-induced immune responses and intestinal barrier function.
View Article and Find Full Text PDFProtective Effects of Spondias mombin L. Juice Alone or in Combination With Lactobacillus acidophilus in 5-Fluorouracil-Induced Experimental Intestinal Mucositis.
Neurogastroenterol Motil
December 2024
Postgraduate Program in Oral Sciences, Postgraduate Program in Pharmaceutical Sciences, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal, Brazil.
Background: Evaluate the impact of Spondias mombin L. juice (SM), alone and in combination with Lactobacillus acidophilus, in an experimental model of intestinal mucositis.
Methods: Swiss mice were orally administered with saline, SM, or SM combined with L.
Whole-genome sequencing and genomic analysis of four strains newly isolated from human feces.
Front Microbiol
December 2024
West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Background: Numerous studies have demonstrated that is closely associated with human health. These bacteria colonize the mucus layer of the gastrointestinal tract and utilize mucin as their sole source of carbon and nitrogen. spp.
View Article and Find Full Text PDFGinsenoside Ro improves Salmonella Typhimurium-induced colitis through inhibition of the virulence factors SopB and SopE2 via the RAC1/CDC42/ARP2/3 pathway.
FASEB J
December 2024
State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine Jilin University, Center of Infectious Diseases and Pathogen Biology, Department of Infectious Diseases, First Hospital of Jilin University, Changchun, China.
Salmonella enterica serovar Typhimurium (S. Typhimurium) poses a serious threat to human and animal health, and there is an urgent need to develop new therapeutic agents. In our in vivo study, ginsenoside Ro (Ro) reduced the mortality rate of S.
View Article and Find Full Text PDF[Mechanism of Huangqin Decoction in repairing intestinal barrier of ulcerative colitis by regulating tryptophan metabolism and activating AhR].
Zhongguo Zhong Yao Za Zhi
October 2024
the First Dongguan Affiliated Hospital of Guangdong Medical University Dongguan 523710, China the Second Clinical Medical College, Guangdong Medical University Dongguan 523808, China.
This study aims to elucidate the mechanism of Huangqin Decoction(HQD) in treating ulcerative colitis(UC) by investigating the relationship between tryptophan metabolism and intestinal barriers. In the in vivo experiments, 3% dextran sulfate sodium(DSS) was used to induce a mouse model of acute colitis, with mesalazine as a positive control. The therapeutic effect of HQD on mice with UC was evaluated according to body weight, disease activity index(DAI), colon length, and pathological changes.
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