To discover new natural resources with biological effects, the chemical investigation of antioxidant and antimicrobial activities of extract's isolated from roots of . Gas chromatography-mass spectrometry (GC-MS) analysis demonstrated the presence of the major chemical constituents present in the methanol extract (1,3-oxathiolane, 1,3-cyclopentadiene, 5-(1-methylethylidene), 5,9-hexadecadienoic acid, methyl ester, decane), chloroform extract (acetic acid, diethoxy-, ethyl ester, 2,2-bis(ethylsulfonyl)propane, 3-methyl-2-(2-oxopropyl) furan), and hexane extract (3-hexanone, 4,4-dimethyl, decane,2,6-dimethyldecane, decane, 2,4,6-trimethyl, decane, 2,4,6-trimethyl, 1-butanesulfinamide, 1,1,2,2,3,3,4,4,4-nonafluoro-N-methyl, decane). The total compound identified (56.2%) in chloroform extract, (54.72%) in hexane extract, and (65%) in methanol extract. The antioxidant effects were performed using diphenylpicrylhydrazyl radical (DPPH). The results showed that the methanol extract showed significantly the highest anti-DPPH with an IC value of 37.61 ± 1.37 g/mL, followed by chloroform and hexane extracts with IC values of 40.82 ± 3.60 and 45.20 ± 2.54 g/mL, respectively. The antifungal activity of extracts was evaluated against pathogens fungi including , , , and . Methanolic and chloroform extracts showed maximum inhibition against all test pathogens, while hexane extract showed minimum inhibition.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825229PMC
http://dx.doi.org/10.1155/2022/1388850DOI Listing

Publication Analysis

Top Keywords

methanol extract
12
hexane extract
12
gc-ms analysis
8
extract
8
chloroform extract
8
decane 246-trimethyl
8
analysis antioxidant
4
antioxidant antifungal
4
antifungal studies
4
extracts
4

Similar Publications

Background: The global prevalence of diabetes among adults over 18 years of age is expected to increase from 10.5% to 12.2% (between 2021 and 2045).

View Article and Find Full Text PDF

The present experimental study aimed to assess the wound healing and anti-inflammatory effects of green synthesized copper nanoparticles (CuNPs) by the methanol extract of (Boiss), as a plant with various pharmacological effects, such as anti-inflammatory and antimicrobial effects, in traditional and modern medicine. The precipitation approach was used for the green synthesis of CuNPs by mixing the methanol and copper sulfate solution. Cell viability and fibroblast proliferation assay were performed by MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide) assay.

View Article and Find Full Text PDF

Antinociceptive and anti-inflammatory activities of the methanol extract of Korovin in a rat model.

Arch Razi Inst

June 2024

Department of Pharmacy Practice, Faculty of Pharmacy, University of Sindh, Jamshoro, Pakistan.

Today, the current chemical agents used for the management of pain cause numerous complications. They are associated with the occurrence of disorders in the digestive system, damage to the kidney, or addiction, which has prompted individuals to seek novel drugs that, apart from removing the side effects, are cost-effective and available. The present survey aimed to assess the antinociceptive and anti-inflammatory activity of Korovin methanolic extract (FEME) in male Swiss mice.

View Article and Find Full Text PDF

Evaluation of PFAS extraction and analysis methods for biosolids.

Talanta

December 2024

Interdisciplinary Ecological Sciences & Engineering, Purdue University, West Lafayette, IN, 47907, USA; Department of Environmental & Ecological Engineering, Purdue University, West Lafayette, IN, 47907, USA; Department of Agronomy, Purdue University, West Lafayette, IN, 47907, USA. Electronic address:

Per- and polyfluoroalkyl substances (PFAS) in the environment is a growing concern leading to a focus on PFAS occurrence in biosolids, a byproduct of wastewater treatment processes, often applied to improve soil health. This led to the need for analytical method development for assessing PFAS in biosolids. This study compares three methods for PFAS quantitation, evaluating solvent extraction, clean-up techniques, and final injection solvents.

View Article and Find Full Text PDF

Introduction: is the gram-negative, facultative intracellular bacterium that causes the disease known as plague. Due to the risk for aerosol transmission, a low infectious dose, and the acute and lethal nature of pneumonic plague, research activities with require Biosafety Level 3 (BSL-3) facilities to provide the appropriate safeguards to minimize accidental exposures and environmental release. However, many experimental assays cannot be performed in BSL-3 due to equipment availability, and thus require removal of samples from the BSL-3 laboratory to be completed.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!