Korsakoff's syndrome (KS) is an insidious and progressive neuropsychiatric disorder that affects specific neurocognitive functioning, especially in tasks that require sustained attention, memory, executive functions, and visuospatial functioning. Usually, this disease generates neuropsychiatric complications that worsen the quality of life (QOL) of patients in the medium term. We present a case of a 63-year-old male who presented with a diagnosis of advanced Korsakoff's syndrome and has a clinical history of recurrent memory loss and a history of alcohol abuse. The patient showed difficulty manipulating immediate information, associated with a possible frontal lobe dysfunction, and inability to remember material given through the auditory pathway. The patient showed a psychiatric clinical picture which is constantly worsening his and his immediate caregiver's QOL. The data obtained demonstrate that the patient presents a progressive cognitive impairment, which in the short term is correlated with Korsakoff-type dementia. It is suggested to carry out functional neurorehabilitation plans aimed at improving the QOL of the patient, his immediate caregiver, and future people with this type of diagnosis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825214PMC
http://dx.doi.org/10.1155/2022/2772594DOI Listing

Publication Analysis

Top Keywords

korsakoff's syndrome
12
advanced korsakoff's
8
syndrome clinical
8
patient
5
neuropsychiatric alterations
4
alterations patient
4
patient diagnosed
4
diagnosed advanced
4
clinical case
4
case low
4

Similar Publications

Wernicke's encephalopathy, the acute phase of Wernicke-Korsakoff syndrome, is characterised as a triad of altered mental status, ocular signs and ataxia. Our patient presented with hyperemesis gravidarum, which is a rare aetiology of Wernicke's encephalopathy. The patient did not have any oculomotor abnormalities, which are more common and classically described in Wernicke's triad.

View Article and Find Full Text PDF
Article Synopsis
  • * This review examines the effectiveness of non-pharmacological interventions for apathy across different conditions similar to KS, including dementia, Parkinson's disease, schizophrenia, and traumatic brain injury, drawing on 22 systematic reviews and 32 empirical studies.
  • * Successful interventions for severely cognitively impaired individuals rely on external stimulation rather than intrinsic motivation, highlighting the need to tailor treatments to the individual's interests and assess the specific apathetic behaviors before starting any intervention.
View Article and Find Full Text PDF

Social norms in Korsakoff's syndrome and alcohol-related dementia.

J Clin Exp Neuropsychol

November 2024

Department of Neurology and Alzheimer Center Erasmus MC, Erasmus MC University Medical Center, Rotterdam, the Netherlands.

Article Synopsis
  • Social cognition is crucial for interpreting social information, and this study examined its impairment in individuals with Korsakoff's syndrome (KS) and alcohol-related dementia (ARD) compared to healthy controls.
  • The study included 30 KS patients, 10 ARD patients, and 74 matched controls, using the Social Norms Questionnaire to measure social cognition.
  • Results indicated that both KS and ARD patients struggled more with judging social norms than controls, with KS patients making significantly more judgment errors, highlighting the social behavior challenges faced by these patients.
View Article and Find Full Text PDF

Relationship between alcohol consumption and cognitive impairment in the adult population over 60 years of age: A systematic review.

Rev Colomb Psiquiatr (Engl Ed)

November 2024

Instituto de Neuropsiquiatría y Adicciones (INAD), Centros Asistenciales Dr. Emili Mira i López (CAEMIL-Recinto Torribera), Parc de Salut Mar, Santa Coloma de Gramenet, Barcelona, Spain.

Article Synopsis
  • Alcohol consumption is linked to cognitive impairment in individuals aged 60 and older, with both excessive and moderate drinking influencing cognitive health.
  • A systematic review of studies from 2010 to 2020 identified that excessive and prolonged alcohol use can lead to serious forms of dementia and cognitive impairment, citing notable disorders like Wernicke-Korsakoff syndrome.
  • The cognitive functions most impacted by alcohol use disorder include executive functions, visuospatial skills, attention, and memory, emphasizing the risks associated with high levels of alcohol intake.
View Article and Find Full Text PDF

Beyond the Liver: Neurologic Manifestations of Alcohol Use.

Clin Liver Dis

November 2024

Department of Internal Medicine, University of South Dakota Sanford School of Medicine, 1400 West 22nd Street, Sioux Falls, SD 57105, USA; Division of Hepatology, Avera McKennan Hospital & University Health Center, 1315 South Cliff Avenue, Suite 1200 Plaza 3, Sioux Falls, SD 57105, USA. Electronic address:

Article Synopsis
  • Alcohol use not only harms the liver but also significantly affects the nervous system, often mimicking hepatic encephalopathy, making diagnosis challenging.
  • It disrupts neurotransmitter balance, especially between gamma-aminobutyric acid and glutamate, and chronic use, along with thiamine deficiency, leads to long-term neurological issues.
  • Alcohol-related neurological disorders range from acute symptoms like intoxication and withdrawal to chronic conditions such as Korsakoff syndrome, dementia, and peripheral neuropathy, emphasizing the need for careful diagnosis through medical history and exams.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!