Aedes aegypti is closely related to human behavior that allows its establishment through the accumulation of urban solid waste where it lays resistant eggs. Generally, adulticides and larvicides are applied in excess, without ovicidal alternatives, and some household products can help reduce the abundance of quiescent eggs in breeding sites by affecting the viability of eggs. A community involved in prevention and control is one of the most effective strategies for adequate vector management. In this investigation, new alternative strategies for the control of Ae. aegypti are assessed, valuing in laboratory the eggs' response to diverse household products. Susceptibility to different doses of bleach, oil, salt, sodium bicarbonate, vinegar, coffee, garlic, peroxide, and alcohol was measured, as well as its duration over time. New home products were found as alternative ovicidal method. Bleach and sunflower oil had an ovicidal effect at their maximum doses and at almost all of the evaluation times. In contrast, vinegar and coffee had no ovicidal effect at any time, turning out to be stimulators of hatching in the laboratory. These alternative and complementary applications could optimize the surveillance and control of Ae. aegypti in the area, allowing new approaches to reduce populations by eliminating eggs on human microhabitats.
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http://dx.doi.org/10.1016/j.actatropica.2022.106813 | DOI Listing |
J Chem Theory Comput
January 2025
Laboratory of Medicinal Chemistry, Rega Institute for Medicinal Research, Herestraat 49, Box 1030, Leuven B-3000, Belgium.
Synthetic nucleic acids, also defined as xenobiotic nucleic acids (XNAs), opened an avenue to address the limitations of nucleic acid therapeutics and the development of alternative carriers for genetic information in biotechnological applications. Two related XNA systems of high interest are the α-l-threose nucleic acid (TNA) and (3'-2') phosphonomethyl threosyl nucleic acid (tPhoNA), where TNAs show potential in antisense applications, whereas tPhoNAs are investigated for their predisposition toward orthogonal genetic systems. We present predictions on helical models of TNA and tPhoNA chemistry in homoduplexes and in complex with native ribose chemistries.
View Article and Find Full Text PDFVet Dermatol
January 2025
Department of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.
Background: Antimicrobial resistance is increasing each year. For example, in 2019 it was directly responsible for an estimated >1 million deaths. Additionally, the development of new drugs is much slower, generating enormous concerns about responses to infection in the future health scenario.
View Article and Find Full Text PDFClin Case Rep
February 2025
Personalized Precision Health Systems Foundation Bengaluru Karnataka India.
A 42-year-old female with left nasal blockage, facial numbness, upper palate pain, and headache was diagnosed with fungal ball sinusitis via CT scan. Refusing surgery, she opted for Ayurveda. Comprehensive treatment led to complete symptom resolution and a clear CT scan at 3 months.
View Article and Find Full Text PDFiScience
January 2025
Department of Electrical and Computering Engineering, Binghamton University, Binghamton, NY 13902, USA.
Our recent research on type-I quadrature parity-time (PT) symmetry, utilizing an open twin-beam system, not only enables observing genuine quantum photonic PT symmetry amid phase-sensitive amplification (PSA) and loss in the presence of Langevin noise but also reveals an additional classical-to-quantum (C2Q) transition in noise fluctuations. In contrast to the previous setup, our exploration of an alternative system assuming no loss involves a type-II PSA-only scheme. This scheme facilitates dual opposing quadrature-PT symmetry, offering a comprehensive and complementary comprehension of C2Q transitions and PT-enhanced quantum sensing with optimal performance in the symmetry unbroken region.
View Article and Find Full Text PDFRev Cardiovasc Med
January 2025
Department of Radiology, Affiliated Hospital of North Sichuan Medical College, 637000 Nanchong, Sichuan, China.
Dilated cardiomyopathy (DCM) is the ultimate manifestation of the myocardial response to various genetic and environmental changes and is characterized mainly by impaired left ventricular systolic and diastolic function. DCM can ultimately lead to heart failure, ventricular arrhythmia (VA), and sudden cardiac death (SCD), making it a primary indication for heart transplantation. With advancements in modern medicine, several novel techniques for evaluating myocardial involvement and disease severity from diverse perspectives have been developed.
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