This article focuses on predefined time synchronization problem for a class of signal switching neural networks with time-varying delays. In the network models, we not only consider the coupling characteristics in the following networks, but also consider the disturbance with standard Brownian motion. In the design of the controller, the control gain is designed as 1ɛ+T-t (t∈[T,T), ɛ is an optional smaller positive number), which avoids the infinite gain (the control gain is designed as 1T-t in other reference). In order to get the predefined time control law, a power function is multiplied to the Lyapunov functional, from which it can get an exponential upper bound function via the derivative and mathematical expectation operation. Utilizing the martingale theory and the method of Laplace matrix, some novel predefined time synchronization criteria are obtained for the leader-following neural networks, meanwhile the following networks can maintain the leader network after achieved synchronization. Based on the special network of the main system, five corollaries separately develop the predefined time synchronization results from different perspectives. An example with some simulation figures and computing results fully exhibits the effectiveness of the achieved synchronization scheme. In this case, although the error signal is disturbed by Brownian motion, the trace signal can still stably converge to zero by this control scheme, meanwhile the predefined-time control effect is achieved.
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http://dx.doi.org/10.1016/j.neunet.2022.12.024 | DOI Listing |
Front Pharmacol
January 2025
Department of Pharmacy, Tianjin First Central Hospital, Tianjin, China.
Background: Obinutuzumab was approved in China in June 2021 used in combination with chemotherapy (followed by obinutuzumab maintenance) for the treatment of adult patients with previously untreated stage II bulky, III, or IV follicular lymphoma (FL). The clinical application of obinutuzumab has recently begun in China, but there is a lack of evidence to determine under which circumstances it should be considered the treatment of choice. A comprehensive assessment is necessary to evaluate the efficacy, safety, and cost-effectiveness of obinutuzumab in adult patients with FL.
View Article and Find Full Text PDFFront Pharmacol
January 2025
Phase I Clinical Trial Site, Nanjing Gaoxin Hospital, Nanjing, Jiangsu, China.
Background: Fluticasone propionate is a synthetic trifluoro-substituted glucocorticoid, a highly selective glucocorticoid receptor agonist. Fluticasone propionate nebuliser suspensions is an inhaled corticosteroid with the low systemic bioavailability which provides a low risk (benefit outcome without the adverse effects that accompany systemically administered corticosteroids), referred as a first-line preventive agent for patients with persistent asthma. China has become one of the countries with the highest asthma mortality rate in the world in the past years.
View Article and Find Full Text PDFJ Biopharm Stat
January 2025
Department of Mathematics, The University of Manchester, Manchester, UK.
Biomarkers are measured repeatedly in clinical studies until a pre-defined endpoint, such as death from certain causes, is reached. Such repeated measurements may present a dynamic process for understanding when to expect the study's endpoint. Joint modelling is often employed to handle such a model.
View Article and Find Full Text PDFJ Dermatolog Treat
December 2025
Dermatology Department, King Fahad Hospital Jeddah, Jeddah, Saudi Arabia.
Objective: This systematic review evaluates the efficacy of minoxidil alone versus minoxidil with low-level laser therapy (LLLT) for androgenic alopecia.
Study Design: systematic review and meta-analysis.
Methods: An online search of PubMed, Web of Science, and MEDLINE was conducted.
JSES Int
November 2024
Department of Orthopedics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Background: No questionnaire is currently available for use in patients with shoulder pain in an Indonesian-speaking population. This study aimed to translate the Oxford Shoulder Score (OSS) into Indonesian and assess its validity and reliability for use in Indonesian-speaking patients with shoulder pain.
Methods: After a forward and backward translation procedure, the validity and reliability of the questionnaire were investigated.
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