AI Article Synopsis
- - The study examines the epidemiology of central nervous system (CNS) cancers in Iran from 1990 to 2019 to address the lack of comprehensive data for effective healthcare planning and resource allocation.
- - Utilizing data from the Global Burden of Disease 2019, key measures such as incidence, mortality, and disability-adjusted life years (DALYs) were analyzed, showing significant burden with 5,811 new cases and 3,494 deaths reported in 2019.
- - Results indicate a rising trend in CNS cancer incidence across all demographics, while mortality rates have largely stabilized, particularly notable in patients under 15 years, emphasizing the need for targeted healthcare strategies.
Article Abstract
Introduction: Central nervous system cancers (CNS cancers) impose a significant burden upon healthcare systems worldwide. Currently, the lack of a comprehensive study to assess various epidemiological indexes of CNS cancers on national and subnational scales in Iran can hamper healthcare planning and resource allocation in this regard. This study aims to fill this gap by providing estimates of CNS cancer epidemiological measures on national and subnational levels in Iran from 1990 to 2019.
Materials And Methods: This study is a part of Global Burden of Disease (GBD) 2019 that contains epidemiological measures including prevalence, incidence, mortality, Disability-Adjusted Life Years (DALYs), Years Lived with Disability (YLDs), and Years of Life Lost (YLLs) of CNS cancers. Age standardization was utilized for comparing different provinces.
Results: In 2019, 5811 (95% Uncertainty Interval: 2942-7046) national new cases and 3494 (1751-4173) deaths due to CNS cancers were reported. National age-standardized incidence (ASIR), deaths (ASDR), and DALYs rates were 7.3 (3.7-8.8), 4.6 (2.3-5.5), and 156.4 (82.0-187.0) per 100,000 in 2019, respectively. Subnational results revealed that ASDR and ASIR have increased in the past 30 years in all provinces. Although incidence rates have increased in all age groups and genders since 1990, death rates have remained the same for most age groups and genders except for young patients aged under 15, where a decrease in mortality and YLLs can be observed.
Conclusion: The incidence, deaths, and DALYs of CNS cancers increased at national and subnational levels. These findings should be considered for planning and resource allocation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134290 | PMC |
| http://dx.doi.org/10.1002/cam4.5553 | DOI Listing |
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