AI Article Synopsis
- * Diagnosis of CJD involves assessing clinical symptoms alongside brain imaging, electroencephalogram results, and cerebrospinal fluid analysis for specific markers.
- * A case study of a 53-year-old patient in Fortaleza, Brazil, confirmed a probable diagnosis of sporadic CJD using tests for 14-3-3 protein and RT QUIC analysis, ruling out other similar conditions.
Article Abstract
Unlabelled: Prion diseases are an important cause of rapidly progressive dementias. Among them, the most common is sporadic Creutzfeldt-Jakob disease (CJD). It is a rare and incurable disease, with rapid progression to death.
Objective: To describe the diagnostic approach of a patient with Creutzfeldt-Jakob disease.
Methods: The diagnosis is established through the clinical picture associated with characteristic changes in the brain magnetic resonance imaging, the electroencephalogram, and analysis of specific changes in the cerebrospinal fluid.
Results: The present report describes the case of a 53-year-old patient in the city of Fortaleza-CE. The diagnosis was made based on the clinical condition and through diagnostic tests, including 14-3-3 protein and RT QUIC analysis. Differential diagnosis was performed with other rapidly progressive causes, such as infectious and immune-mediated diseases.
Conclusions: The diagnosis of probable sporadic CJD was established.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762391 | PMC |
| http://dx.doi.org/10.1590/1980-5764-DN-2021-0110 | DOI Listing |
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