AI Article Synopsis
- - The study analyzes a soil sample from an industrial area in Bahadurgarh, India, identifying a new bacterial strain named sp. KD18 through morphological methods and genomic sequencing.
- - Using the Illumina Nextseq500 platform, researchers generated a genome of 7.2 Mb and discovered 25 biosynthetic gene clusters, with a notable focus on the potential for industrial and pharmaceutical applications of lipstatin.
- - The metabolite analysis confirmed the production of lipstatin, and the genome sequence has been submitted to the NCBI database for public access.
Article Abstract
Unlabelled: The present study scrutinizes the presence of strains in the soil sample collected from industrial area of Bahadurgarh (Haryana) India. The morphological approach manifested the isolated strain belong to species and named as sp. KD18. Sequencing of sp. KD18 genome was performed by Illumina Nextseq500 platform. 65 contigs were generated via SPAdes v3.11.1 and harboured genome size of 7.2 Mb. AntiSMASH server revealed the presence of 25 biosynthetic gene clusters in KD18 genome where BGC of lipstatin was of more interest from industrial and pharmaceutical purpose. The draft genome sequence represented via ANI values claimed that the KD18 strain belongs to and finally named as KD18. The LC-MS analysis of the extracted metabolite confirmed the production of lipstatin. The genome sequence data have been deposited to NCBI under the accession number of
Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-022-03453-3.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810780 | PMC |
| http://dx.doi.org/10.1007/s13205-022-03453-3 | DOI Listing |
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