AI Article Synopsis
- This study presents an effective method for synthesizing α-carbonyl sulfones by combining α-aryl-α-diazoesters with sulfonyl hydrazides.
- The reaction uses Copper(I) iodide (CuI) and DBU, making the process efficient and cost-effective.
- The approach is notable for its mild reaction conditions, allowing for a straightforward reaction using stable and inexpensive starting materials.
Article Abstract
A facile synthesis of α-carbonyl sulfones has been accomplished by the cross-coupling of α-aryl-α-diazoesters with sulfonyl hydrazides in the presence of CuI and DBU. The reaction employs inexpensive and bench stable sulfonyl hydrazides as a sulfonyl source, and facilitates the migratory insertion with α-aryl-α-diazoesters under mild reaction conditions.
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| http://dx.doi.org/10.1039/d2ob02219b | DOI Listing |
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