Cannabigerol (CBG) is a non-psychoactive phytocannabinoid present in the L. plant. In our study, CBG at the concentration of 10 µM was used to treat NSC-34 motor neuron-like cells. The aim of the study was to evaluate the effects of CBG on NSC-34 cells, using next-generation sequencing (NGS) technology. Analysis showed the activation of the WNT/planar cell polarity (PCP) pathway and Ephrin-Eph signaling. The results revealed that CBG increases the expression of genes associated with the onset process of cytoskeletal remodeling and axon guidance.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823669 | PMC |
| http://dx.doi.org/10.3390/plants12010193 | DOI Listing |
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