AI Article Synopsis
- The revised post-Cardiac Arrest Syndrome for Therapeutic hypothermia (rCAST) score is designed to predict neurologic outcomes and mortality in out-of-hospital cardiac arrest (OHCA) patients, but it hasn't been widely tested outside Japan.
- The study analyzed 108 post-cardiac arrest syndrome patients who underwent targeted temperature management, finding that 49.1% were classified as low severity according to the rCAST score.
- Results indicated the rCAST score has moderate accuracy for predicting poor neurologic outcomes and mortality at day 28, mainly showing that only low-severity patients had favorable neurologic outcomes.
Article Abstract
The revised post-Cardiac Arrest Syndrome for Therapeutic hypothermia (rCAST) score was proposed to predict neurologic outcomes and mortality among out-of-hospital cardiac arrest (OHCA) patients. However, it has rarely been validated outside Japan. Therefore, this study aimed to investigate this issue. All adult patients admitted to our medical intensive care unit for targeted temperature management (TTM) between July 2015 and July 2021 were enrolled. Their medical records were retrieved, and rCAST scores were calculated. A total of 108 post-cardiac arrest syndrome (PCAS) patients who received TTM were analyzed. According to the rCAST score, 49.1%, 50.0%, and 0.9% of the patients were classified as low, moderate, and high severity, respectively. The areas under the curves for the rCAST score were 0.806 (95% confidence interval [CI]: 0.719-0.876) and 0.794 (95% CI: 0.706-0.866) to predict poor neurologic outcomes and mortality at day 28, respectively. In contrast to the original report, only low-severity patients had favorable neurologic outcomes. The rCAST score showed moderate accuracy in our OHCA patients with PCAS who received TTM to predict poor neurologic outcomes and mortality at day 28.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821639 | PMC |
| http://dx.doi.org/10.3390/jcm12010242 | DOI Listing |
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