Material characterization at moderate strain rates is an important factor for improving the adequacy and accuracy of analysis of structures operating under extreme conditions. In this paper, the deformation and fracture of Ti-5Al-2.5Sn alloys were studied utilizing the punch test at strain rates up to several hundred per second. Loading velocities from 0.0003 to 15 m/s were realized during the spherical body penetration through a thin titanium plate. To describe the plastic flow and fracture of the Ti-5Al-2.5Sn alloy at strain rates ranging from 0.001 to 10 s, a micromechanical damage model was coupled with a viscoplastic constitutive model based on the dislocation dynamics. Numerical simulations of the punch test at 15 and 2 m/s were carried out to validate used constitutive relations. It was verified that the simulated fracture shape and deflections were similar to experimental ones. It was found that dynamic punch test is suitable for validation of damage kinetics under complex stress states.
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http://dx.doi.org/10.3390/ma16010416 | DOI Listing |
Acta Clin Belg
January 2025
Internal Medicine department, UZ Brussel, Internal Medicine Research Group, Vrije Universiteit Brussel, Brussels, Belgium.
Objectives: Urinary tract infections (UTIs) are an important cause of empiric antibiotic (over)treatment at the emergency department (ED). To enhance empiric antibiotic choices, mapping the national and local microbiology and antimicrobial resistance (AMR) patterns is crucial. This study aims to examine resistance patterns at a Brussels ED and to identify risk factors for AMR to evaluate current treatment guidelines and help combat AMR.
View Article and Find Full Text PDFFront Microbiol
December 2024
National Key Laboratory of Germplasm Innovation and Utilization of Horticultural Crops, National Fruit Free-Virus Germplasm Resource Indoor Conservation Center, Department of Horticulture and Forestry, Huazhong Agricultural University, Wuhan, China.
Global citrus production has been severely affected by citrus Huanglongbing (HLB) disease, caused by Candidatus Liberibacter asiaticus (Clas), and the development of effective control methods are crucial. This study employed antimicrobial lipopeptide and phytohormone complex powder (L1) prepared from the fermentation broth of the endophytic plant growth promoting bacterium (PGPB) of strain MG-2 to treat Liberibacter asiaticus (Las)-infected ' 'Chun Jian' plants. Real-time fluorescence quantitative polymerase chain reaction (qPCR) and PCR were employed for disease detection.
View Article and Find Full Text PDFCureus
December 2024
Clinical Microbiology, Prathima Institute of Medical Sciences, Karimnagar, IND.
Introduction Intestinal carriage of multidrug-resistant organisms (MDROs) in healthy populations could amplify resistant bacteria, which may increase the risk of infections by these bacteria in the community and in the hospital. This study investigated the prevalence of colonization of multidrug-resistant (MDR) bacteria in the intestines of healthy individuals in South India. Methods A prospective study was conducted for six months at a tertiary care teaching hospital.
View Article and Find Full Text PDFVet Res
January 2025
Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.
Glutathione reductase (GR) plays a pivotal role in managing oxidative stress, a process crucial for microbial virulence and adaptation, yet it has not been extensively explored in bacteria such as Avibacterium paragallinarum (Av. paragallinarum). This study examined the specific roles of GR in Av.
View Article and Find Full Text PDFMol Syst Biol
January 2025
Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 24, 72076, Tübingen, Germany.
Metabolic variation across pathogenic bacterial strains can impact their susceptibility to antibiotics and promote the evolution of antimicrobial resistance (AMR). However, little is known about how metabolic mutations influence metabolism and which pathways contribute to antibiotic susceptibility. Here, we measured the antibiotic susceptibility of 15,120 Escherichia coli mutants, each with a single amino acid change in one of 346 essential proteins.
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