Special Techniques of Adjuvant Breast Carcinoma Radiotherapy.

Cancers (Basel)

Department of Oncology and Radiotherapy, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Charles University, 500 05 Hradec Králové, Czech Republic.

Published: December 2022

AI Article Synopsis

  • - Modern radiotherapy techniques aim to minimize radiation exposure to healthy tissues, leading to fewer side effects and faster recovery times for patients.
  • - Randomized studies show that increasing the radiation dose specifically to the tumor area during whole breast irradiation (WBI) can enhance treatment effectiveness, reducing the traditional treatment time from 5-7 weeks to just 3-4 weeks with hyperfractionated regimens.
  • - Accelerated partial breast irradiation (APBI) allows for a shorter treatment timeline and less radiation to healthy tissue, using methods like intraoperative radiation, brachytherapy, or external beam radiotherapy, while still achieving acceptable cosmetic results, especially in patients undergoing immediate breast reconstruction.

Article Abstract

Modern radiotherapy techniques are designed to permit reduced irradiation of healthy tissue, resulting in a diminished risk of adverse effects and shortened recovery times. Several randomized studies have demonstrated the benefits of increased dosage to the tumor bed area in combination with whole breast irradiation (WBI). Conventional WBI treatment following breast-conserving procedures, which required 5-7 weeks of daily treatments, has been reduced to 3-4 weeks when using hyperfractionated regimens. The dosage administration improves local control, albeit with poorer cosmesis. The method of accelerated partial breast irradiation (APBI) shortens the treatment period whilst reducing the irradiated volume. APBI can be delivered using intraoperative radiation, brachytherapy, or external beam radiotherapy. Currently available data support the use of external beam partial breast irradiation in selected patients. Modern radiotherapy techniques make it possible to achieve favorable cosmesis in most patients undergoing immediate breast reconstruction surgery, and studies confirm that current methods of external beam radiation allow an acceptable coverage of target volumes both in the reconstructed breast and in the regional lymphatic nodes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818986PMC
http://dx.doi.org/10.3390/cancers15010298DOI Listing

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